金匮温经汤结合口服地屈孕酮治疗黄体功能不全致不孕不育的临床观察

目的:研究金匮温经汤结合口服地屈孕酮治疗黄体功能不全致不孕不育的临床疗效。方法:选取2014年3月至2015年3月我院接诊的80例黄体功能不全致不孕不育患者作为本次研究对象。对照组采取金匮温经汤进行治疗,观察组采取金匮温经汤结合口服地屈孕酮进行治疗,观察2组患者治疗后内分指标泌E2、P情况、子宫内膜厚度、妊娠情况、治疗疗效情况。结果:治疗后,观察组E2、P(138.90±30.02)pg/m L、(11.92±3.01)ng/m L均优于对照组(120.01±30.21)pg/m L、(9.21±2.91)ng/m L,差异有统计学意义(P0.05);观察组子宫内膜厚度(0.92±0.21)cm优于对照组(0.71±0.23)cm,差异有统计学意义(P0.05);观察组妊娠率87.50%(35/40)优于对照组50.00%(20/40),差异有统计学意义(P0.05);观察组总有效率95.00%(38/40)优于对照组70.00%(28/40),差异有统计学意义(P0.05);结论:金匮温经汤结合口服地屈孕酮治疗黄体功能不全致不孕不育的临床疗效显著,能够改善患者的黄体功能,提高妊娠成功率。

Clinical Observation on Jingui Wenjing Decoction combined with Oral Progesterone Acetate in Treatment of Infertility Caused by Luteal Insufficiency

To Study the clinical effect of DWM decoction combined with oral progesterone acetate in the treatment of infertility caused by luteal insufficiency. Methods:Eighty cases of patients with luteal function caused by incomplete infertility from March 2014 to March 2015 treated in the hospital were researched. Patients in the control group took Jingui Wenjing Decoction, while patients in the observation group adopted Jingui Wenjing decoction combined with oral progesterone acetate treatment. Secretion of E2, P condition, endometrial thickness, pregnancy, treatment efficacy of the two groups after the treatment were observed. Results:After treatment, E2 and P (138.90±30.02)pg/mL, (11.92±3.01)ng/mL of the observation group were better than those of the control group (120.01±30.21)pg/mL, (9.21±2.91)ng/mL, with statistically significant difference (P<0.05). Endometrial thickness of the observation group (0.92±0.21)cm was better than that of the control group (0.71±0.23)cm, showed that the difference was statistically significant (P<0.05). Pregnancy rate in the observation group was 87.50% (35/40), which was better than that the control group of 50.00% (20/40) and the difference was statistically significant (P<0.05). The total effective rate of the observation group was 95.00% (38/40) and was supior to that of the control group of 70.00% (28/40), indicating that the difference was statistically significant (P<0.05). Conclusion:Jingui Wenjing Decoction combined with oral progesterone acetate in the treatment of infertility caused by luteal insufficiency may have obvious clinical curative effect and improve patients with corpus luteum function and increase pregnancy rate.