米非司酮联合五加生化胶囊治疗人工流产不全效果评价

目的:研究米非司酮联合五加生化胶囊治疗对人工流产不全的效果。方法:将316例人工流产吸刮术后不全流产患者随机分为3组,治疗组给予米非司酮联合五加生化胶囊治疗,清宫组给予二次清宫治疗,对照组予五加生化胶囊治疗疗,观察3组患者治疗效果及月经恢复情况。结果:治疗组、对照组、清宫组治疗有效率分别为81.1%(86/106)、52.3%(55/105)和93.3%(98/105),差异有统计学意义(P0.05);两两比较显示,对照组治疗有效率明显低于治疗组和清宫组,治疗组治疗有效率明显低于清宫组,差异有统计学意义(P均0.05)。治疗组、清宫组、对照组治疗后阴道出血时间分别为(9.3±2.6)d、(10.3±3.4)d和(13.6±4.8)d,差异有统计学意义(P0.01);两两比较显示,治疗组治疗后阴道出血时间明显少于清宫组和对照组,清宫组治疗后阴道出血时间明显少于对照组,差异有统计学意义(P0.05)。治疗组、清宫组、对照组治疗后月经复潮时间分别为(27.6±4.4)d、(34.5±5.6)d和(36.8±7.2)d,差异有统计学意义(P0.01);两两比较显示,治疗组治疗后月经复潮时间明显少于清宫组和对照组,清宫组治疗后月经复潮时间明显少于对照组,差异有统计学意义(P0.05)。3组不良反应发生率相比较差异无统计学意义。结论:米非司酮联合五加生化胶囊用于人工流产不全治疗,效果良好,不良反应小,治疗后的月经恢复较再次清宫及中药组时间短,值得临床推广应用。

Efficacy Assessment of Mifepristone Combined Wujia Shenghua Capsule in the Treatment of Incomplete Artificial Abortion

To research the effect of mifepristone in combination with Wuwei Shenghua capsule in the treatment of incomplete artificial abortion. Methods: A total of 316 cases of incomplete suction evacuation abortion were were randomly divided into three groups. The treatment group was given mifepristone combined with Wujia Shenghua capsule, uterus curettage group was given a second curettage, and the control group was given only Wujia Shenghua capsule. To observe the therapeutic effect and menstruation recovery duration of patients in 3 groups. Results: The total effective rate of treatment group, curettage group and control group were 81.1% (86/106), 52.3% (55/105) and 93.3% (98/105) respectively, and the difference was statistically significant (P<0.05). Also, the hemorrhage duration in the treatment group was shorter than those of the curettage group and control group, and the difference was statistically significant (P<0.05). The hemorrhage duration of the curettage group was also shorter than that of the control group with statistical difference (P<0.05). The menstruation restore duration are (9.3 ±2.6)d, (10.3±3.4) d and (13.6 ±4.8) d respectively in the treatment group, curettage group and control group, and the difference was statistically significant (P<0.01). The comparison on adverse reactions among the three groups show no statistical difference. Conclusion: Mifepristone combined with Wujia Shenghua capsule is effective in treating incomplete abortion, which has less side effects. It is worthy of market promotion.