脉络舒通丸治疗精索静脉曲张的临床疗效与安全性分析

目的:探究脉络舒通丸对精索静脉曲张患者的治疗效果及安全性。方法:选取2018年11月至2019年4月青岛市市立医院收治的精索静脉曲张患者120例作为研究对象,按照随机数字表法随机分为对照组和观察组,每组60例。2组患者均通过腹腔镜精索静脉高选择结扎术治疗,对照组给予阿司匹林肠溶片治疗,观察组患者在对照组治疗的基础上给予脉络舒通丸治疗。比较2组患者术后疗效、精液质量及并发症发生情况。结果:观察组治愈率达93.33%,对照组为76.67%,2组比较差异有统计学意义(P<0.05);观察组总有效率为96.67%,对照组为90.00%,2组比较差异无统计学意义(P>0.05)。观察组患者治疗6个月后的精液量、精子密度都高于对照组,液化时间和畸形率都低于对照组,2组比较差异均有统计学意义(P<0.05)。观察组患者的总并发症发生率为6.7%,显著低于对照组的26.7%,2组比较差异有统计学意义(P<0.05)。结论:脉络舒通丸可显著改善精索静脉曲张患者术后精液质量,降低复发率和并发症发生率,为临床治疗提供思路。

Clinical Efficacy and Safety Analysis on Mailuo Shutong Pills in the Treatment of Varicocele

To explore efficacy and safety of Mailuo Shutong Pills in patients with varicocele.Methods:A total of 120 patients with varicocele admitted in Qingdao Municipal Hospital from November 2018 to April 2019 were selected as study objects, and randomly divided into control group and observation group, with 60 cases in each group.Both groups were treated with high-selectivity ligation of spermatic vein by laparoscope.The control group was given Aspirin Enteric-coated Tablets, on the basis of this, patients in the observation group were given Mailuo Shutong Pills.After the operation, the quality of semen, recurrence and complications were compared between the 2 groups.Results:The cure rate in the observation group was 93.33%, and that in the control group was 76.67%.The difference between the 2 groups was statistically significant(P<0.05).The total effective rate in the observation group was 96.67%, and that in the control group was 90.00%.There was no statistical difference between the 2 groups(P>0.05).After 6 months of the treatment, semen volume and sperm density in the observation group were higher than those in the control group, and liquefaction time and deformity rate were lower than those in the control group.The differences between the 2 groups were statistically significant(P<0.05).The total incidence of complications in the observation group was 6.7%, which was significantly lower than 26.7% in the control group.The difference between the 2 groups was statistically significant(P<0.05).Conclusion:Mailuo Shutong Pills can significantly improve the quality of postoperative semen in patients with varicocele, reduce the recurrence rate and the incidence of complications, and provide ideas for clinical treatment.