复方丹参滴丸治疗早期糖尿病视网膜病变的疗效

目的:观察复方丹参滴丸对早期糖尿病视网膜病变的治疗效果。方法:将82例2型糖尿病并发糖尿病视网膜病变患者随机分为治疗组(48例)和对照组(34例)。2组均给予降糖、降脂和降压类药物常规治疗,治疗组加用复方丹参滴丸(天士力制药集团股份有限公司),3次/d,15粒/次口服,疗程为24周;2组患者在治疗前后分别检查空腹血糖、糖化血红蛋白、肝肾功能以及眼底镜行眼底检查、眼底照相、眼底造影等,以观察糖尿病眼底病变的变化情况。结果:治疗组和对照组的眼底病变均较治疗前好转,差异有统计学意义(P0.05),且治疗组的微血管瘤、出血斑、渗出及黄斑水肿情况较对照组改善更明显,差异有统计学意义(P0.05)。结论:常规治疗加用复方丹参滴丸可以更显著地减少DR患者眼底微血管瘤数目、眼底出血面积、眼底硬(软)性渗出和眼底黄斑水肿面积。

The Curative Effect of Compound Danshen Dripping Pills Treatment Early Diabetic Retinopathy

To observe the curative effect of compound Danshen dripping pills(CDDP) treatment early diabetic retinopathy.Methods:A total of 82 patients of type 2 diabetes mellitus with diabetic retinopathy were randomly divided into treatment group(48cases)and the control group(34 cases).All patients were receive conventional therapy which give hypoglycemic agent,lipid-lowering drugs, Antihypertensive drugs,we add CDDP (Tianjin Tasly)to the treatment group,15 grain,tid,oral for 24 weeks;Two groups of patients all need to check the Fasting blood glucose,glycosylated hemoglobin,liver and kidney function,Ophthalmoscope fundus examination,eye-ground photography,fundus fluorescein angiography before and after treatment,In order to observe the change of diabetic retinal pathological changes.Results:The fundus lesions of the treatment group and control group both show better before treatment,differences are statistically significant(P<0.05).And the microangioma,blood spots,Seepage and macular edema in the treatment group improved more obvious,Differences are statistically significant(P<0.05).Conclusion:Conventional treatment combined with compound danshen dropping pill can more significantly reduce the number of fundus micro hemangioma,eyeground hemorrhage area, fundus hard(soft) seepage and fundus macular edema area in DR patients.