复方紫草油治疗尿布皮炎的疗效观察

目的:探讨复方紫草油治疗婴幼儿尿布皮炎的临床疗效。方法:选取2015年8月至2017年2月开封市儿童医院收治的尿布皮炎患者100例,按照随机数字表法随机分为对照组和观察组,每组50例。在用药前和用药后,分别对中重度尿布皮炎患儿皮损处用消毒棉签取样,并进行细菌培养,观察菌检结果。对照组患儿常规给予氧化锌油,观察组患儿使用复方紫草油,比较2组治疗后的总体疗效,伴创面感染患儿皮损面积评分,红斑及糜烂消退时间以及不良反应情况。结果:观察组患儿治疗的疗效优于对照组,差异有统计学意义(P 0. 05)。治疗后,菌检结果观察组1例阳性,对照组7例阳性,观察组菌检结果明显优于对照组,差异有统计学意义(P 0. 05)。治疗后,观察组皮损面积评分低于对照组,观察组红斑及糜烂消退时间小于对照组,差异均有统计学意义(P 0. 05)。2组不良反应发生率比较,差异无统计学意义(P0. 05)。结论:复方紫草油治疗婴幼儿尿布皮炎疗效确切,安全性高,不良反应小,值得临床推广和应用。

Curative Effects of Compound Radix Lithospermi Oil on Diaper Dermatitis

To explore the curative effects of Compound Radix Lithospermi Oil on diaper dermatitis.Methods:A total 100 cases of diaper dermatitis in Children''s Hospital of Kaifeng City from August 2015 to February 2017 were selected.The patients were divided into observation group (50 cases) and control group (50 cases) by random number table.Before and after treatment,disinfection cotton swabs were used to sample the skin lesions of the children with moderate and severe diaper dermatitis,and bacterial culture was conducted to observe the bacterial test results.Children in the control group were routinely given zinc oxide oil,while those in the observation group were treated with Compound Radix Lithospermi Oil.The overall efficacy of the two groups was compared,and the skin loss area score,erythema and erosion resolution time and adverse reactions of the children with wound infection were compared between the two groups.Results:The curative effect of the observation group was better than that of the control group,and the difference was statistically significant (P<0.05).After treatment,there were one case in observation group and seven cases in control group were positive,the bacteria inspection results in the observation group was significantly better than that in control group.The difference was statistically significant (P<0.05).After treatment,the skin lesion area score of the observation group was lower than that of the control group,and the erythema and erosion resolution time of the observation group was lower than that of the control group,both the differences were statistically significant (P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion:Compound Radix Lithospermi Oil is effective in treating infantile diaper dermatitis with high safety and less side effects,which is worthy of clinical promotion and application.