| 基于AMPK的中药有效成分治疗2型糖尿病的研究进展 |
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| 引用本文： | 田会萍,姚鸿萍,王思文,马侗,封卫毅.基于AMPK的中药有效成分治疗2型糖尿病的研究进展[J].世界中医药,2016(11). |
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| 作者姓名： | 田会萍 姚鸿萍 王思文 马侗 封卫毅 |
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| 作者单位： | 西安交通大学第一附属医院药学部，西安，710061 |
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| 基金项目： | 2015年陕西省自然科学基金面上项目（编号：2015JM8447）——二甲双胍与细胞毒药物脂质体对肿瘤干细胞引起肿瘤复发和转移研究 |
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| 摘 要： | 腺苷酸活化蛋白激酶(AMP-activated Protein Kinase,AMPK)在调节细胞和全身代谢中发挥着重要作用,是研究治疗2型糖尿病药物的关键靶点。本文介绍了AMPK的结构及调节方式,并通过检索文献,对通过调节AMPK及其相关信号通路干预2型糖尿病的中药有效成分进行归纳总结。
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| 关 键 词： | 腺苷酸活化蛋白激酶 AMPK信号通路 2型糖尿病 中药 |
| 收稿时间： | 2016/2/14 0:00:00 |
Research Progress on Traditional Chinese Medicine in Treatment of Type 2 Diabetes Based on AMPK |
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| Tian Huiping,Yao Hongping,Wang Siwen,Ma Tong,Feng Weiyi.Research Progress on Traditional Chinese Medicine in Treatment of Type 2 Diabetes Based on AMPK[J].World Chinese Medicine,2016(11). |
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| Authors: | Tian Huiping Yao Hongping Wang Siwen Ma Tong Feng Weiyi |
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| Abstract: | The AMP-activated protein kinase (AMPK) is a key senor in cellular and systematic metabolism, and has become a key target in research of anti-diabetic drugs. This article is to introduce the structure and regulation mechanism of the AMPK. By literature searching, it is to summarize research progress on traditional Chinese medicine in the treatment of type 2 diabetes based on the AMP-activated protein kinase and related signaling pathway. |
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| Keywords: | AMP-activated protein kinase AMPK signaling pathway Type 2 diabetes Chinese Materia Medica |
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