温阳利水化淤法联合腹腔化疗治疗胃癌腹膜转移性腹水的疗效分析

目的:研究温阳利水化瘀法联合腹腔化疗治疗胃癌腹膜转移性腹水的临床疗效。方法:选取从2013年2月至2015年7月,于恩施土家族苗族自治州中心医院进行治疗的胃癌腹膜转移性腹水病患92例,采用数字法随机分为观察组和对照组,每组46例。2组患者均给予腹腔化疗治疗,观察组在此基础上加用温阳利水化瘀法治疗,比较2组治疗效果。结果:观察组总有效率为67.39%(31/46),显著高于对照组41.30%(19/46);观察组中医证候总有效率为89.13%(41/46),显著高于对照组的69.57%(32/46);治疗前2组KPS评分比较无明显差异,分别治疗后观察组KPS评分为(82.9±9.4),显著高于对照组的(76.3±7.5);治疗前2组IL-6以及TNF-α水平比较无明显差异,分别治疗后观察组IL-6以及TNF-α水平均显著低于对照组,差异均有统计学意义(P0.05)。结论:温阳利水化淤法联合腹腔化疗治疗胃癌腹膜转移性腹水疗效显著,能显著改善患者症状,安全性好,值得推广应用。

Clinical Study of Wenyang Lishui Huayu Method Combined with Intraperitoneal Chemotherapy in the Treatment of Gastric Cancer with Peritoneal Metastasis Ascites

To study Wenyang Lishui Huayu method combined with intraperitoneal chemotherapy in the treatment of gastric cancer peritoneal metastasis ascites.Methods:A total of 92 cases with peritoneal metastasis ascites induced by gastric cancer admitted in our hospital from February 2013 to July 2015 were collected and randomly divided into the observation group (46 cases) and the control group (46 cases).Patients in the two groups were given intraperitoneal chemotherapy.On that basis, the observation group was given Wenyang Lishui Huayu treatment.The clinical effects of the two methods were compared.Results:The effective rate of the observation group was 67.39% (31/46), which was significantly higher than that of the control group 41.30% (19/46).Besides, in the observation group, the total effective rate was 89.13% (41/46), which was significantly higher than that of the control group 69.57% (32/46).There was no significant difference in KPS scores between the two groups before treatment, but after treatment the KPS score of the observation group was (82.9±9.4), significantly higher than that of the control group (76.3±7.5).Additionally, there were no significant differences in the levels of IL-6 and TNF-in the two groups before treatment, while after treatment, the levels of IL-6 and TNF-in the observation group were significantly lower than those of the control group(P<0.05).Conclusion:Wenyang Lishui Huayu method combined with intraperitoneal chemotherapy in the treatment of gastric cancer peritoneal metastasis ascites has significant curative effect.It can significantly relieve the symptoms of patients, of good safety and is worthy of clinical application.