| 5-溴异苯并呋喃-1(3H)-酮合成方法改进 |
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| 引用本文： | 余红霞,郭峰.5-溴异苯并呋喃-1(3H)-酮合成方法改进[J].中国药物化学杂志,2002,12(6):352-353. |
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| 作者姓名： | 余红霞 郭峰 |
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| 作者单位： | 1. 武汉化工学院制药系,湖北武汉,430073
2. 湖北工学院化工系,湖北武汉,430068 |
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| 摘 要： | 以邻苯二甲酰亚胺为起始原料，经硝化、还原、溴代等步骤。合成5－溴异苯并呋喃－1（3H）－酮，总收率为40%（以邻苯二甲酰亚胺计），纯度达99.6%。
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| 关 键 词： | 合成方法 5－溴异苯并呋喃－1－酮 硝化 还原 溴代 |
| 文章编号： | 1005-0108(2002)06-0352-02 |
Improved synthesis of 5-bromoisobenzofuran-1(3H)-one |
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| YU Hong xia ,GOU Feng.Improved synthesis of 5-bromoisobenzofuran-1(3H)-one[J].Chinese Journal of Medicinal Chemistry,2002,12(6):352-353. |
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| Authors: | YU Hong xia GOU Feng |
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| Institution: | YU Hong xia 1,GOU Feng 2 |
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| Abstract: | In this article,phthalimide was chosen as the start material.The 5 bromoisobenzofuran 1(3 H ) one was obtained via nitration,reduction and bromination,the overall yield was 40% and the purity of the product was 99 6%. |
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| Keywords: | bromoisobenzofuran 1(3 H ) one nitration reduction bromination |
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