| 两种仙人掌多糖对肿瘤细胞膜脂流动性的影响 |
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| 引用本文： | 胡齐莉,冯治宇.两种仙人掌多糖对肿瘤细胞膜脂流动性的影响[J].中国现代中药,2006,8(11):17-19. |
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| 作者姓名： | 胡齐莉 冯治宇 |
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| 作者单位： | 哈药集团中药三厂,黑龙江,哈尔滨,150078 |
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| 摘 要： | 目的:研究仙人掌多糖对S180荷瘤小鼠肿瘤细胞膜脂流动性的影响。方法:采用荧光分光光度法进行研究。结果:仙人掌多糖可使小鼠肿瘤细胞的膜微粘度上升,膜脂流动下降。结论:仙人掌多糖降低肿瘤细胞膜脂流动性,改变肿瘤细胞膜信号转导功能,阻断恶性信号的循环转导实现药物抗肿瘤作用。
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| 关 键 词： | 仙人掌多糖 膜脂流动性 |
| 收稿时间： | 08 25 2006 12:00AM |
| 修稿时间： | 2006年8月25日 |
Effect of Two Cactus Polysaccharides on Membrane Lipid Fluidity of S180 Tumor-bearing Mice |
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| Hu Qili and Feng Zhiyu.Effect of Two Cactus Polysaccharides on Membrane Lipid Fluidity of S180 Tumor-bearing Mice[J].Modern Chinese Medicine,2006,8(11):17-19. |
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| Authors: | Hu Qili and Feng Zhiyu |
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| Affiliation: | The 3^rd traditional Chinese medicine Factory of Harbin Pharmaceutical Group, Harbin Heilongjiang 150078, China |
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| Abstract: | Objective: To study the effect of polysaccharide of cactus on S_ 180 cell membrane lipid fluidity. Methods: By fluorescence spectrophotometry.Results: Polysacchrides of cactus increase S_ 180 cell microviscosity and decrease membrane lipid fluidity of S_ 180 cell membrane. Conclusion: Polysacchrides of Cactus decrease lipid fluidity of S_ 180 cell membrane, change the function of tumor cell signal transduction and communication to play a key role in anti-tumor. |
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| Keywords: | Cactus Polysaccharides Membrane lipid fluidity |
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