| 候选转移抑制基因（MTSS1）与肿瘤关系的研究进展 |
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| 引用本文： | 罗小邹,洪育明.候选转移抑制基因（MTSS1）与肿瘤关系的研究进展[J].山东医大基础医学院学报,2014(1):79-83. |
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| 作者姓名： | 罗小邹 洪育明 |
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| 作者单位： | 福建医科大学附属第二医院耳鼻咽喉科,福建泉州362000 |
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| 摘 要： | 肿瘤转移抑制基因的表达产物——转移消失蛋白是一种肌动蛋白结合蛋白，广泛表达于多种组织，而在转移性肿瘤中，其表达缺失。，在细胞发生发展以及肿瘤的侵袭和转移中，MTSS1发挥着重要作用。着重从肿瘤转移抑制基因的结构、生物学功能以及其与肿瘤转移的关系做一综述。
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| 关 键 词： | 肿瘤转移抑制基因 肿瘤 MTSS1 MIM |
Progress of candidate metastasis-suppressor gene and tumor. |
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| LUO Xiao-zou,HONG Yu-ming.Progress of candidate metastasis-suppressor gene and tumor.[J].Journal of Preclinical Medicine College of Shandong Medical University,2014(1):79-83. |
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| Authors: | LUO Xiao-zou HONG Yu-ming |
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| Institution: | . (Department of Oto- rhinolaryngology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou 362000, Fujian, China) |
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| Abstract: | Expression product of tumor metastasis suppressor gene（ MTSS1 ） is an actin-binding protein which is widely expressed in many tissues but not metastatic tumors. MTSS1 plays important roles in the process of cell growth, tumor invasion and metastasis,. This article focuses on the structure, biological function and relationship of tumor metastasis suppressor gene with tumor metastasis. |
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| Keywords: | Tumor metastasis suppressor gene Tumor MTSS1 MIM |
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