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Gut microbial communities modulating brain development and function
Authors:Al-Asmakh Maha  Anuar Farhana  Zadjali Fahad  Rafter Joseph  Pettersson Sven
Affiliation:Department of Microbiology; Tumor and Cell Biology; Karolinska Institutet; Huddinge, Sweden; Department of Biomedical Science; College of Arts and Sciences; Qatar University; Doha, Qatar·
Abstract:Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous microbiota which has been shown to affect developmental programming of the brain. This may have consequences for brain maturation and function that impact on cognitive functions later in life. This review discusses these recent findings from a developmental perspective.
Keywords:behavior   brain development   gut microbiota   microbiota-gut-brain axis   probiotics
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