Gut microbial communities modulating brain development and function |
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Authors: | Al-Asmakh Maha Anuar Farhana Zadjali Fahad Rafter Joseph Pettersson Sven |
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Affiliation: | Department of Microbiology; Tumor and Cell Biology; Karolinska Institutet; Huddinge, Sweden; Department of Biomedical Science; College of Arts and Sciences; Qatar University; Doha, Qatar· |
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Abstract: | Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous microbiota which has been shown to affect developmental programming of the brain. This may have consequences for brain maturation and function that impact on cognitive functions later in life. This review discusses these recent findings from a developmental perspective. |
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Keywords: | behavior brain development gut microbiota microbiota-gut-brain axis probiotics |
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