抗—HBcIgM在HBV感染55例中的动态观察

本文ELLSA检测,对55例HBV感染者血清中的抗-HBcIgM随访研究其动态变化。结果发现,急性乙肝35例抗-HBcIgM的阳性率在入院时,6个月,12个月分别为100%（35/35）,86%（31/36）,及34%（6/18）,提示抗-HBcIgM在6个月大都保持阳性,至12个月大部分消失;“无症状”携带者20例抗-HBcIgM阳性率在首检时,6个月,24个月都为100%（各为20/20,17/17,及10/10）,提示“无症状”携带者的抗-HBcIgM很难自然消失,同时把抗-HBcIgM和HBsAg检测对比,提示HBsAg阴性不能排除急性乙肝的诊断。

Follow-up Observation of Anti-HBcIgM in 55 Cases Infected by HBV

Fifty five cases infected by HBV Were Studied. Their serum anti-HBcIgM detected by ELISA method was observed and followed up from January 1988 to December 1989. It Was found that the Positive percentages of anti-HBcIgM in 35 cases of acute hepatitis B on admission, in the 6th month and 12th month were 100% (33/35), 86% (31/36)and 34% (6/18)respectively. It is suggested that the anti-HBcIGM Within 6 months after acute infection was mostly positive and eradicated in most cases in the 12th month. It was also found that the anti-HBcIgM of "Symptomless"HBV carriers at the first out-patient department examination, 6th month and 24th month were all 100% positive (20/20, 17/17 and 10/10 respectively). It showed that anti-HBcIgM in "Symptomless"HBV carriers could rarely disappear naturally. The test of anti-HBcIgM when compared to that of HBsAg suggested that in HBsAg-negative hap- atitis patients the diagnosis of hepatitis B could hardly be ruled out.