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Molecular diagnosis of a vascular prosthesis infection, due to Propionibacterium acnes, by amplification and sequencing of 16S rDNA
Authors:L Le Page  I Podglajen  E Chemla  J L Mainardi
Institution:UnitéMobile de Microbiologie Clinique, Clinical Microbiology, Hôpital Européen Georges Pompidou, 20–40 rue Leblanc, 75908 Paris cedex 15 and;Cardiovascular Surgery, Hôpital Européen Georges Pompidou, Paris, France;Tel: +33 156 09 39 51 Fax: +33 156 09 24 46 E-mail:
Abstract:We describe a case of indolent vascular prosthesis infection due to Propionibacterium acnes. The microorganism was identified only by amplification and sequencing of 16S rDNA, while standard cultures remained negative. This observation underscores the usefulness of molecular techniques for the diagnosis of infection caused by fastidious microorganisms.
Keywords:Vascular prosthesis              Propionibacterium acnes            16S rDNA amplification
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