Tri-dimensional automatic segmentation of PET volumes based on measured source-to-background ratios: influence of reconstruction algorithms. |
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| Authors: | Jean-Fran?ois Daisne Mérence Sibomana Anne Bol Thomas Doumont Max Lonneux Vincent Grégoire |
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| Affiliation: | Department of Radiation Oncology, Laboratory of Radiobiology, Université catholique de Louvain, St-Luc University Hospital, 10 Ave Hippocrate, B-1200 Brussels, Belgium. |
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| Abstract: | A method for automatic volume segmentation of functional imaging based on a relationship between source-to-background ratio and the iso-activity level to be used is described. Such method, which has been established with radioactive spheres in a phantom, is independent of the a priori knowledge of the lesion of interest and is valid for small (>2 ml) and/or poorly contrasted (S/B>1.5) lesions. Accuracy varies slightly with the image reconstruction algorithm used. |
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