临床药师在普外科围手术期预防用抗菌药物中的作用探讨

目的:探讨临床药师在普外科围手术期合理预防性应用抗菌药物中的作用。方法:整群选取药师深入普外科参与临床药物治疗前后的颈胸组Ⅰ类切口手术出院病例,对其围手术期预防用抗菌药物合理性进行分析评价,以考查临床药师的工作效果。结果:药师参与临床药物治疗前后,抗菌药物应用率由100.00%下降为46.30%(P<0.05);用药频次由1.65次/例下降为0.67次/例;抗菌药物合理应用率由0.00%上升为69.44%(P<0.05);围手术期不合理应用抗菌药物的表现形式均有不同程度改善;平均抗菌药物费用由988.17元下降为118.50元。结论:药师深入临床参与药物治疗有效地提高围手术期抗菌药物的合理应用水平,同时为进一步探讨临床药师工作模式提供了有益参考。

Roles of clinical pharmacists in prophylactic use of antibiotics during perioperative period in department of general surgery

Objective: To evaluate the roles of clinical pharmacists in prophylactic use of antibiotics during perioperative period in department of general surgery.Methods: Cluster cases of type I incision operation were selected,and divided into two groups,one was before and another was after pharmacists’ involvement in clinical medication.The data of medication in two groups were collected and compared.Results: After clinical pharmacists’ involvement in drug treatment,application rate of antibiotics decreased from 100.00% to 46.30%(P<0.05) and the frequency of medication decreased from 1.65 times per case to 0.67 times per case.The rational application rate of antibiotics was significantly increased from 0.00% to 69.44%(P<0.05).Unreasonable application manifestations of perioperative antibiotics were reduced,and the average cost of antibiotics declined from 988.17 yuan to 118.50 yuan after pharmacists involve into clinical medication treatment.Conclusion: The clinical pharmacists’ in-depth participation in drug treatment will effectively improve the perioperative rational use of antibiotics,and also provided a useful reference to further investigations for the mode of clinical pharmacists’ work.