Critical flicker frequencies in MS patients with normal or abnormal pattern VEP |
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Authors: | Tapani Salmi |
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Affiliation: | Department of Clinical Neurophysiology, Helsinki University Central Hospital, Helsinki, Finland |
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Abstract: | Critical flicker frequencies (CFF) were compared with the latencies of visual pattern reversal evoked potentials (VEP) in 2 groups of MS patients to evaluate the value of CFF in electrophysiological diagnostics of demyelination of the optic tract. A microprocessor-based device was constructed to obtain CFF thresholds with a 2-alternative forced-choice method. VEP latency was more frequently pathological than CFF, but CFF was abnormal in 2 optic neuritis patients with normal VEP. The frequency of pathological CFF and VEP was different in the patient group with a long history of MS compared with the new cases; in the freshly diagnosed group, CFF had a better diagnostic yield compared to the patients with a longer history. |
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Keywords: | CFF forced choice method MS VEP |
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