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Selective Deletion of CD8+ Cells Upregulated by Caspases-1 via IL-18 in Mice Immunized with Major Outer Membrane Protein of Shigella dysenteriae 1 Following Infection
Authors:Ashim Kumar Bagchi  Ajoy Kumar Sinha  Rushita Adhikari  Pradip Maiti  Joydeep Mukherjee  Arpita Panda  Dhira Rani Saha
Affiliation:(1) Research & Development Division, Nutratech, Inc., Winnipeg, MB, R3Y 1M5, Canada;(2) Division of Immunology and Vaccine Development, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata-10, India;(3) Department of Physiology, University of Manitoba, Winnipeg, MB, R3E 0J9, Canada;(4) School of Environmental Studies, Jadavpur University, Kolkata-32, India;(5) Division of Electron Microscopy, National Institute of Cholera and Enteric Diseases, Beliaghata, Kolkata-10, India;(6) Institute of Cardiovascular Sciences, St. Boniface Research Centre, 351 Tache Avenue, Winnipeg, MB, R2H 2A6, Canada;(7) Present address: Department of Experimental Hematology, NSCB Cancer Research Institute, Kolkata, India
Abstract:

Introduction  

Mucosal lymphoid changes were observed in cryopreserved rectal tissues obtained from BALB/c mice infected with Shigella dysenteriae 1, immunized with 57-kDa major antigenic outer membrane protein, and infection after immunization.
Keywords:
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