皮肤磨削术联合表皮细胞膜片治疗稳定期白癜风疗效观察

目的:观察皮肤磨削术联合应用表皮细胞膜片治疗稳定期白癜风的疗效,探讨治疗稳定期白癜风的有效治疗方式。方法:在术前2~3周,切取稳定期白癜风患者耳沟后0.5cm2皮肤,进行表皮细胞的分离、培养,制成表皮细胞膜片,色素脱失部位行皮肤磨削术达创面呈点状渗血,覆盖表皮细胞膜片,愈邦及无菌敷料包扎固定,直至外层敷料逐渐脱落,创面愈合。结果:所有患者创面均一期愈合,无感染等并发症发生,后期色泽明显改善,接近周围正常皮肤,未出现瘢痕增生或挛缩。结论:皮肤磨削术联合应用表皮细胞膜片治疗部分稳定期白癜风创面愈合快,后期色泽等整体改善明显,瘢痕增生不明显。

Clincal therapy for the stable vitiligo combined dermabrasion with epidermal cell patch

Objective Observed the treatment effect of stable vitiligo combined dermabrasion with epidermal cell patch, explore the effective surgical treatment of stable vitiligo. Methods About the size of 0.5cm2 skin was cut from the ear ditch of stable vitiligo patients 2N3 weeks preoperation, Isolated, cultured, made the epidermal cell patch. When the skin of vitiligo was grinded to the punctate bleeding, the epidermal cell patch was Covered on the wound with other sterile dressing. Wound healed afer the dressing dropped. Results All the wound healed well, there were no complication such as Infection, the late color looks much better, which was closed to the surrounding normal skin, and there was no apparent scar contracture. Conclusions The wound healed fast for the stable vitiligo combined dermabrasion with epidermal cell patch, the late color looks much better and the scar was not obvious.