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A Model for Predicting Field-Directed Particle Transport in the Magnetofection Process

Authors:	Edward P. Furlani Xiaozheng Xue

Affiliation:	(1) Dept. Chemical & Biological Engineering, University at Buffalo (SUNY), 614 Furnas Hall, Buffalo, New York 14260-4200, USA;(2) Dept. of Electrical Engineering, University at Buffalo (SUNY), 614 Furnas Hall, Buffalo, New York 14260-4200, USA

Abstract:	Purpose To analyze the magnetofection process in which magnetic carrier particles with surface-bound gene vectors are attracted to target cells for transfection using an external magnetic field and to obtain a fundamental understanding of the impact of key factors such as particle size and field strength on the gene delivery process.

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