玻璃体切割联合玻璃体腔注药治疗外伤性眼内炎36例

研究外伤性眼内炎的病原及玻璃体切割术联合玻璃体腔注药治疗外伤性眼内炎的临床疗效分析。方法：对临床病历资料完整的36例行玻璃体切割联合玻璃体腔注药治疗外伤性眼内炎患者资料进行整理分析，比较患者术前术后视力，分析受伤原因及病原体培养结果。结果：随访5~36mo，行玻璃体切割联合玻璃体腔注药的36例患者术后感染均得到有效控制，24例患者视力有不同程度提高，占67%。球内异物是最主要的致病原因。22例术中取玻璃体行微生物学检查，7例检查阳性，其中革兰氏阳性球菌3例，革兰氏阴性杆菌1例，真菌2例，混合感染1例。结论：玻璃体切割联合玻璃体腔注药是治疗外伤性眼内炎的有效方法，玻璃体腔内注入有效药物是提高外伤性眼内炎治愈率的关键

Clinical analysis for the treatment of post-traumatic infectious endophthalmitis with vitrectomy and intravitreal drugs

AIM:To evaluate the efficacy of vitrectomy in combination with intravitreal drugs perfusion in the management of post-traumatic endophthalmitis and summarize the pathogen cultured by the vitreous samples.METHODS:Thirty-six eyes diagnosed as post-traumatic infectiouis endophthalmitis were analyzed retrospectively from March 2002 to October 2011.All the patients underwent vitrectomy in combination with intravitreal drugs perfusion and were followed up for 5 to 36 months.The visual acuity,traumatic causes and microorganisms culture were analyzed.RESULTS:There was significant reduction in inflammation after surgery.Infectious symptoms were completely controlled in all the cases.Final visual acuity were improved in 67% of cases(24/36).Foreign body was the most common cause(67%) among traumatic causes.24 patients underwent bacterial and fungal culture,only 32%was positive.Gram-positive cocci was the commonest microorganism.CONCLUSION:Vitrectomy in combination with intravitreal drugs perfusion is an effective and safe method in the treatment of post-traumatic infectious endophthalmitis.Effective intravitreal drug is the key point of the therapy.