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| Wernicke-Geschwind语言模型的fMRI初步检验 | |
| 引用本文： | 赵小虎,王培军,李春波,杨振燕,王金红,胡正辉,毛新清. Wernicke-Geschwind语言模型的fMRI初步检验[J]. 中国医学影像技术, 2004, 20(12): 1836-1838 |
| 作者姓名： | 赵小虎 王培军 李春波 杨振燕 王金红 胡正辉 毛新清 |
| 作者单位： | 1. 同济大学附属同济医院影像科,上海,200065;浙江大学物理系交叉学科实验室 2. 同济大学附属同济医院影像科,上海,200065 3. 浙江大学物理系交叉学科实验室 |
| 摘 要： | 目的利用fMRI方法检验经典的Wernicke-Geschwind语言模型.方法以Block Design设计模式,对10名正常中国人的听觉性语言(词语水平)功能进行BOLD磁共振脑功能成像,并与经典的Wernicke-Geschwind语言模型进行比较与检验.结果所有受试者均完成了实验要求,且头动范围小于1个像素大小.语言任务激活的脑区包括:双侧颞上回、双侧运动区(前后运动区及辅助运动区)、双侧小脑半球及视皮层,左侧颞横回、左侧角回,右侧颞中回及以及扣带回后部.结论经典的语言模型存在较明显的不足与缺陷,需要进一步完善. |
| 关 键 词： | 听觉性语言 功能性磁共振成像 Wernicke-Geschwind模型 研究设计 |
| 文章编号： | 1003-3289(2004)12-1836-03 |
| 收稿时间： | 2004-09-12 |
| 修稿时间： | 2004-09-12 |
Preliminary fMRI explore of the Wernicke-Geschwind model of language |
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| ZHAO Xiao-hu,WANG Pei-jun,LI Chun-bo,YANG Zhen-yan,WANG Jin-hong,HU Zheng-hui and MAO Xin-qing. Preliminary fMRI explore of the Wernicke-Geschwind model of language[J]. Chinese Journal of Medical Imaging Technology, 2004, 20(12): 1836-1838 | |
| Authors: | ZHAO Xiao-hu WANG Pei-jun LI Chun-bo YANG Zhen-yan WANG Jin-hong HU Zheng-hui MAO Xin-qing |
| Affiliation: | Imaging Department of Tongji Hospital of Tongji University, Shanghai 200065, China;Imaging Department of Tongji Hospital of Tongji University, Shanghai 200065, China;Imaging Department of Tongji Hospital of Tongji University, Shanghai 200065, China;Imaging Department of Tongji Hospital of Tongji University, Shanghai 200065, China;Imaging Department of Tongji Hospital of Tongji University, Shanghai 200065, China;Imaging Department of Tongji Hospital of Tongji University, Shanghai 200065, China |
| Abstract: | Objective To preliminarily testify the classical language model of Wernicke Geschwind with BOLD fMRI. Methods Ten healthy native Chinese underwent blood oxygenation level dependent (BOLD) contrast functional magnetic resonance imaging (fMRI) on a 1.5T system when they were listening actively to emotionally neutral words. Results Compared with classical language model of Wernicke Geschwind,different cortical areas associated with auditory language were found. The activation areas included bilateral superior temporal gyrus,bilateral motor cortex, bilateral cerebellum,bilateral visual cortex and left angular gyrus,left temporal transversal gyrus, right middle temporal gyrus and right posterior cingulum. Conclusion Classical language model of Wernicke Geschwind has some deficits and needs to be improved. |
| Keywords: | Auditory language Functional magnetic resonance imaging Wernicke-Geschwind model Research design |
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