八正散加减方治疗湿热下注型慢性前列腺炎排尿症状的临床研究

目的:研究八正散加减方治疗湿热下注型慢性前列腺炎排尿症状的临床疗效。方法:选取湿热下注型慢性前列腺炎患者72例,随机分为治疗组(八正散加减方)和对照组(八正散)。2组疗程均为28d,观察患者美国国立卫生研究院慢性前列腺炎症状评分(NIH-CPSI)、中医症状评分、最大尿流率及前列腺按摩液(EPS)常规检查的变化情况。结果:治疗组临床痊愈6例,显效10例,有效9例,无效6例,总有效率80.6%;对照组临床痊愈4例,显效10例,有效11例,无效7例,总有效率78.1%。两组对中医症状评分、NIH-CPSI及EPS均有改善(P<0.05),治疗组在改善排尿症状方面与对照组相比有统计学差异(P<0.05)。结论:八正散加减方治疗湿热下注型慢性前列腺炎有较好疗效,能改善患者的临床症状,有明显改善排尿症状作用。

Modified Bazhengsan for urination symptoms of chronic prostatis with damp-heat accumlated in the lower jiao

Objective:To study the clinical effects of the modified formula of Bazhengsan on the urination symptoms of chronic prostatis with damp-heat accumulated in the lower jiao. Methods:A total of 72 chronic prostatitis patients with damp-heat accumulated in the lower jiao were equally randomized to receive the modified formula of Bazhengsan (the trial group) and the primal Bazhengsan (the control group),both for a course of 28 days. Then we observed the changes in the NIH-CPSI scores,scores on Traditional Chinese Medicine (TCM) syndrome,maximum flow rate of urine (MFR) and results of the expressed prostatic secretion test (EPS).Results:Among the 31 patients of the trial group,6 were cured,10 achieved excellent results,9 got improved,and 6 failed to respond,with a total efficacy rate of 80.6%. While in the control group,4 were cured,10 achieved excellent results,11 got improved,and 7 failed to respond,with a total efficacy rate of 78.1%. Significant improvement was observed in NIH-CPSI scores,TCM syndrome and EPS results in both of the groups (P<0.05),and the trial group showed significant difference from the control in the improvement of urination symptoms (P<0.05). Conclusion:Modified Bazhengsan is effective in the treatment of chronic prostatis with damp-heat in the lower jiao. It can significantly improve its clinical symptoms,especially urination symptoms.