| 儿童大骨节病患者血清GOT,ALP及LDH同功酶的测定和分析 |
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| 引用本文： | 莎日,赵洪昌,伊力奇,李淑梅. 儿童大骨节病患者血清GOT,ALP及LDH同功酶的测定和分析[J]. 地方病通报, 1986, 0(3) |
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| 作者姓名： | 莎日 赵洪昌 伊力奇 李淑梅 |
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| 作者单位： | 内蒙古自治区地方病防治研究所 呼和浩特市(莎日，赵洪昌，伊力奇)，内蒙古自治区地方病防治研究所 呼和浩特市(李淑梅) |
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| 摘 要： | 本文对30名大骨节病患儿,38名病区健康儿童以及34名非病区健康儿童的血清碱性磷酸酶(ALP),谷草转氨酶(GOT)以及乳酸脱氢酶(LDH)同功酶进行了测定分析。结果表明:大骨节病患儿的血清GOT,LDH_1较非病区明显升高,LDH_3相对降低,并在X线出现改变以前就有所变化,而ALP,LDH_2的活性改变不明显。因此,血清GOT,LDH_1,LDH_3等生化指标能够反应出大骨节病患儿的组织细胞损伤情况,对大骨节病的早期诊断和疾病的防治有着重要的意义。
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| 关 键 词： | 大骨节病 同功酶 膜缺损 早期诊断 |
THE DETECTION AND ANALYSIS OF ACTIVITES OF THE PLASMA ALP, GOT AND ISOZYMES OF LDH FROM CHILDREN AFFECTED WITH KASCHIN - BECK''''S DISEASA |
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| Sa-ri et al. THE DETECTION AND ANALYSIS OF ACTIVITES OF THE PLASMA ALP, GOT AND ISOZYMES OF LDH FROM CHILDREN AFFECTED WITH KASCHIN - BECK''''S DISEASA[J]. Endemic Diseases Bulletin, 1986, 0(3) |
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| Authors: | Sa-ri et al |
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| Abstract: | The activities of the plasma ALP, GOT and isozymes of LDH of 30 children affected with Kaschin-Beck's disease, 38 healthy children of Kaschin-Beck's disease affected area and 34 healthy children of non-Kaschin-Beck's disease affected area were determined. The results showed that there were noticeable increases in the activities of plasma GOT, LDH1 and a decrease in the LDH3 of Kaschin - Beck's disease affected children compared with those of healthy children. These changes occurred before radiological changes, this could be used as an index of damage of tissuecells of Kaschin-Beck's disease affected children. This fact may be useful in the early diagnosis of Kaschin-Beck's disease. |
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| Keywords: | Kaschin - Beck's disease-Isozymes-Membrane defect-The early diagnosis |
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