| HPLC测定息痛宁胶囊中秦皮甲素和秦皮乙素的含量 |
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| 引用本文： | 冉兰,曾蓉,晁若冰,吴静.HPLC测定息痛宁胶囊中秦皮甲素和秦皮乙素的含量[J].华西药学杂志,2001,16(2):135-136. |
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| 作者姓名： | 冉兰 曾蓉 晁若冰 吴静 |
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| 作者单位： | 四川大学华西药学院, |
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| 摘 要： | 目的；测定中药复方制剂息痛宁胶囊中有效成份秦皮甲素和秦皮乙素的含量。方法：采用HPLC，ODS柱，流动相为甲醇－水（24：76），检测波长336nm。结果：秦皮甲素进样量在0．005－1．5μg范围内，峰面积与进样量有良好的线性关系，回收率99．9％；秦皮乙素进样量在0．0025－0．75μg范围内，峰面积与进样量有良好的线性关系，回收率102．7％。结论：该方法准确性高，操作简单，可供该制剂的含量测定。
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| 关 键 词： | 秦皮甲素 秦皮乙素 息痛宁胶囊 高效液相色谱法 含量测定 |
| 文章编号： | 1006-0103(2001)02-0135-02 |
| 修稿时间： | 2000年9月1日 |
DETERMINATION OF AESCULIN AND AESCULETIN IN XITONGNING CAPSULE BY HPLC |
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| RAN Lan,ZENG Rong,CHAO Ruo-bing,WU Jing.DETERMINATION OF AESCULIN AND AESCULETIN IN XITONGNING CAPSULE BY HPLC[J].West China Journal of Pharmaceutical Sciences,2001,16(2):135-136. |
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| Authors: | RAN Lan ZENG Rong CHAO Ruo-bing WU Jing |
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| Abstract: | OBJECTIVE:An HPLC was used for determination of aesculin and aesculetion in Xitongning capsule.METHODS:Using HPLC with ODS column and methanol-water(24∶76) pH 3.0 as mobile phase.Samples were detected at 336 nm.RESULTS:Linear ranges were 0.005～1.5 μg(r＝1.0000)for aesculin and 0.0025～0.7 μg(r＝0.9999)for aesculetin.The recoveries were 99.9%(RSD＝1.7%) for aesculin and 102.7%(RSD＝1.1%)for aesculetin.CONCLUSION:The method was simple and accurate and can be used to control the quality of this preparation. |
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| Keywords: | Aesculin Aesculetin Xitongning capsule HPLC |
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