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Malignant melanoma of the choroid in neurofibromatosis.
Authors:R A Wiznia  J K Freedman  A D Mancini  J A Shields
Affiliation:1. Retina Service, Division of Ophthalmology, Department of Surgery, Hospital of St. Raphael, New Haven, Connecticut;2. Department of Medicine, Hospital of St. Raphael, New Haven, Connecticut;3. Oncology Unit, Retina Service, Wills Eye Hospital, Philadelphia, Pennsylvania
Abstract:A 60-year-old white woman with generalized neurofibromatosis and multiple melanocytic hamartomas of the iris developed an unusual choroidal mass, with secondary sensory retinal separation in the left eye. Ophthalmoscopically the tumor had a peculiar donut configuration that was caused by a large focus of central necrosis within a spindle B melanoma.
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