中医西结合治疗带状疱疹临床研究

目的:观察中西医结合治疗带状疱疹的临床疗效。方法:将该院2010年1月—2012年6月收治的带状疱疹患者120例随机分为治疗组和对照组,每组60例患者。对照组单纯给予西药治疗;治疗组患者在西药治疗基础上予中药内服、外用、针灸的中西医结合方法治疗。两组患者均以10 d为1个疗程,共治疗1²个疗程。病情痊愈则不进入下一疗程,疗程结束后随访3个月。比较两组患者症状消失时间、显愈率及后遗神经痛发生率。结果:治疗组平均止痛时间、止疱时间、结痂时间、红斑消退时间和总病程分别为(2.5±0.5)d、(3.4±0.6)d、(4.6±1.1)d、(5.3±1.5)d、(10.1±2.6)d,对照组分别为(5.4±1.3)d、(4.8±1.2)d、(6.6±2.6)d、(8.8±3.7)d、(13.3±3.8)d,治疗组症状消失时间明显短于对照组,经统计学处理有显著性差异(P<0.05或P<0.01)。治疗组显愈率96.7%,后遗神经痛发生1例,占1.7%;对照组显愈率86.7%,后遗神经痛发生9例,占15%。治疗组患者的显愈明显高于对照组,后遗神经痛发生率明显低于对照组,差异有极显著统计学意义(P<0.01)。结论:中西医结合疗法治疗带状疱疹疗程短,治愈率高,后遗症少,值得推广应用。

Clinical Research of Herpes Zoster Treated by Combined Chinese and Western Medicine

Objective：To investigate the clinical efficacy of combined Chinese and Western medicine on herpes zoster. Methods ：A total of 120 patients with herpes zoster were randomly divided into two groups（ n = 60） treatment group and control group. All of them were selected from Jan 2010 to Jun 2012 in our hospital. Control group was treated by simple Western medicine, and treatment group was treated by combined Chinese and Western medicine together. 10 days were 1 course of treatment and the ther- apeutic effects were evaluated after 1 - 2 courses after 3 months followed up. The duration of symptom, the effective rate and re- ducing postherpetie neuralgia were investigated. Results ： The time of pain relief, ceasing new blister, incrustation, erythema fade and general course was （ 2.5 ＋_ 0.5 ） d, （ 3.4 ＋ 0.6） d, （4.6 _＋ 1.1 ） d, （5.3 _＋ 1.5 ） d, （ 10.1 ＋ 2.6） d in the treatment group were significantly shorter than that of（ 5.4 _＋ 1.3 ） d, （4.8 ＋ 1.2） d, （ 6.6 _ 2.6） d, （ 8.8 -＋ 3.7 ） d, （ 13.3 ＋ 3.8 ） d in the control group （P 〈0. 05 or P 〈0. 01 ）. The treatment group effective rate was 96.7%. The incidence of postherpetie neuralgia in 1 case was 1.7%. The observation group effective rate was 86. 7%. The incidence of postherpetic neuralgia in 9 cases was 15%. The effec- tive rate in the treatment group was higher than that in the control group. Contrarily, the incidence of postherpetie neuralgia in the treatment group was lower,there was statistical significance （P 〈 0. 01 ）. Conclusion：Herpes zoster treated by combined Chinese and Western medicine can significantly increase the effective rate, significantly shorten the treatment time and can effectively re- duce the incidence of postherpetie neuralgia. It is safe and reliable, and is well worthy of clinical popularizing and application.