香砂六君子汤治疗功能性消化不良脾胃虚弱型临床观察

目的:观察香砂六君子汤加味治疗功能性消化不良(FD)脾胃虚弱型的临床疗效。方法:将60例FD脾胃虚弱型患者随机分为两组,治疗组30例以香砂六君子汤加味配方颗粒治疗,每日1剂,水冲服,分早晚2次温服。对照组多潘立酮片10 mg,饭前10³0 min服用,每日3次。两组均2周为1个疗程,2个疗程评价疗效。观察两组临床疗效及随访6个月的复发情况。结果:治疗组总有效率90%,对照组总有效率67%,两组比较差异有统计学意义(P<0.05);治疗组亦在症状积分改善方面优于对照组(P<0.05)。结论:香砂六君子汤可提高FD脾胃虚弱型患者临床疗效及改善症状,缩短病程,降低复发率。

Clinical Observation of Xiangsha Liujunzi Decoction in Treatment of Functional Dyspepsia of Spleen-Stomach Deficiency Type

Objective ：To observe the clinical efficacy of Xiangsha Liujunzi Decoction in the treatment of functional dyspepsia （FD） of spleen-stomach deficiency type. Methods ：60 patients with FD of spleen-stomach deficiency type were randomly divided into two groups：treatment group,30 cases treated with Xiangsha Liujunzi Decoction, one dose a day, morning and evening. Control group used domperidone tablets 10 mg,taking 10 ~ 30 min before meals three times a day. Both groups were two weeks as a course of treatment. Clinical efficacy and recurrence during followed-up six months were evaluated. Results ： The total effective rate was 90 % in treatment group and in the control group was 67%, the difference was statistically significant （P 〈 0. 05） ;treatment group also superiorly improved symptom score than the control group （ P 〈0. 05 ）. Conclusion ： Xiangsha Liujunzi Decoction can improve the clinical efficacy and improvement of patients with FD of spleen-stomach deficiency type, shorten the course, and reduce the relapse rate.