|
|||||
|
|
| 血清Na~+浓度对慢性乙型重型肝炎患者预后的评价作用 | |
| 引用本文： | 唐长华,李志彬,刘芳,徐德翠.血清Na~+浓度对慢性乙型重型肝炎患者预后的评价作用[J].实用肝脏病杂志,2010,13(1):31-33. |
| 作者姓名： | 唐长华 李志彬 刘芳 徐德翠 |
| 作者单位： | 1. 武汉医疗救治中心专家组,430023 2. 武汉医疗救治中心临床科室,430023 3. 武汉市第十一医院内科危重症 |
| 基金项目： | 武汉市科技研究项目(WX08D20) |
| 摘 要： | 目的分析慢性乙型重型肝炎患者的血清Na+浓度与预后的关系,比较血清Na+水平、MELD-Na评分与凝血酶原时间(PT)对慢性乙型重型肝炎患者短期预后的预测价值。方法慢性乙型重型肝炎患者85例,分成生存组和死亡组,分别记录患者入院第2天的血清Na+、MELD-Na评分和PT,并分析三者之间的相关性;运用受试者工作特征曲线(ROC)及曲线下面积(AUC)评价血清Na+、MELD-Na评分和PT的预测价值。结果生存组患者血清Na+、MELD-Na评分值和PT分别为136.08±5.66mmol/L,20.42±7.78和22.28±6.37s,死亡组患者血清Na+、MELD-Na分值和PT分别为131.15±6.97mmol/L、34.40±10.72和34.48±10.09s,三项指标均有显著性差异,P0.001。血清Na+与MELD-Na评分值呈显著负相关(r=-0.673,P0.001),血清Na+与PT亦呈负相关(r=-0.238,P0.05),血清Na+浓度、MELD-Na分值和PT的AUC分别为0.261、0.878和0.870。结论低钠血症是影响慢性乙型重型肝炎预后的重要因素,包含血清Na+的MELD-Na评分与PT均能较好地预测慢性乙型重型肝炎患者的短期预后,两者预测能力无显著差异。 |
| 关 键 词： | 慢性乙型重型肝炎 血清Na^＋浓度 MELD—Na评分 凝血酶原时间 预后 |
The concentration of serum sodium in predicting prognosis of patients with chronic severe hepatitis B |
|
| TANG Changhua,LI Zhibin,LIU Fang,et al..The concentration of serum sodium in predicting prognosis of patients with chronic severe hepatitis B[J].Journal of Clinical Hepatology,2010,13(1):31-33. | |
| Authors: | TANG Changhua LI Zhibin LIU Fang |
| Institution: | TANG Changhua,LI Zhibin,LIU Fang,et al. Medical Treatment Center,Wuhan 430023,China |
| Abstract: | Objective To analyze the relationship between the concentration of serum sodium and prognosis of patients with chronic severe hepatitis B,to compare the difference of predictive value between serum sodium,MELD-Na score and prothrombin time (PT). Methods 85 patients with chronic severe hepatitis B were divided into the survival group and death group. The level of serum sodium,PT,MELD-Na score were respectively record-ed after admission,and analyze the correlation between them. Receiver operating characterist... |
| Keywords: | Chronic severe hepatitis B serum sodium MELD-Na score Prothrombin time Prognosis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |