| 大鼠部分肝移植模型的建立 |
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| 引用本文： | 宋康,樊嘉,周俭,祝哲诚,吴志全,邱双健,余耀,黄晓武,汤钊猷. 大鼠部分肝移植模型的建立[J]. 复旦学报(医学版), 2007, 34(2): 307-309 |
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| 作者姓名： | 宋康 樊嘉 周俭 祝哲诚 吴志全 邱双健 余耀 黄晓武 汤钊猷 |
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| 作者单位： | 复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032;复旦大学附属中山医院肝癌研究所,上海,200032 |
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| 摘 要： | 目的 建立大鼠部分肝移植模型.方法 采用雄性SD大鼠,二袖套法行全肝移植和部分肝移植,分析手术情况和术后存活情况.结果 全肝移植组和部分肝移植组2天存活率分别为88%（22/25）和68%（17/25）;1周存活率分别为80%（20/25）和52%（13/25）.结论 大鼠部分肝移植是目前研究活体肝移植和劈离式肝移植肝再生的理想模型,本研究采用改良方法成功建立了大鼠部分肝移植模型.
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| 关 键 词： | 部分肝移植 动物模型 大鼠 |
| 收稿时间： | 2006-09-14 |
| 修稿时间： | 2006-09-14 |
A model of partial liver transplantation in rats |
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| SONG Kang,FAN Jia,ZHOU Jian,ZHU Zhe-cheng,WU Zhi-quan,QIU Shuang-jian,YU Yao,HUANG Xiao-wu,TANG Zhao-you. A model of partial liver transplantation in rats[J]. Fudan University Journal of Medical Sciences, 2007, 34(2): 307-309 |
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| Authors: | SONG Kang FAN Jia ZHOU Jian ZHU Zhe-cheng WU Zhi-quan QIU Shuang-jian YU Yao HUANG Xiao-wu TANG Zhao-you |
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| Abstract: | Purpose To establish a model of partial liver transplantation (PLT) in rats. Methods PLT and full-size liver transplantation (LT) were performed in male SD rats using the two-cuff method. Operation parameters and survival rate were observed and analyzed. Results Two-day survival rate was 88% (22/25) and 68% (17/25), respectively in LT and PLT, and one-week survival rate was 80% (20/25) and 52% (13/25) respectively. Conclusions PLT in rats provides a suitable model for studying liver regeneration in split liver or living donor transplantation. In the study modified techniques were used to establish the model of PLT in rats successfully. |
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| Keywords: | liver transplantation animal models rats |
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