石菖蒲对脑血管性痴呆的益智研究

目的了解石菖蒲对脑血管性痴呆的益智疗效,以为该疾病提供有效的中医药治疗措施。方法将104例血管性痴呆患者随机分为治疗组54例和对照组50例,两组均给予相同的智力训练与精神护理,对照组给予吡拉西坦片治疗,治疗组采用石菖蒲治疗。观察两组治疗前后的临床症状、生命体征,采用改良长谷川式简易智能量表（HDS-R）进行智力评分,评价疗效,观察药物的不良反应。结果经过1个疗程的治疗,两组患者的HDS-R评分均提高,差异有统计学意义（t=0.619、0.506,均P〈0.05）;治疗组治疗后的HDS-R评分显著高于对照组（t=0.425,P〈0.05）。治疗组治疗后的显效率为57.4%,总有效率为90.7%,均显著高于对照组（χ^2=12.421、5.146,均P〈0.05）。治疗组的药物不良反应发生率为9.3%（5/54）,对照组为8.0%（4/50）,差异无统计学意义（χ^2=1.316,P〉0.05）。结论石菖蒲对脑血管性痴呆具有益智作用,具有较高的临床推广价值。

Educational research of acorus gramineus for cerebral vascular dementia

Objective To understand the efficacy of acorus gramineus for cerebral vascular dementia,to provide effective traditional medicine treatment of this dises. Methods 104 cases with cerebral vascular dementia were randomly divided into treatment group in 54 cases and control group in 50 cases.The two groups were treated with the same mental training and mental nursing,the control group was treated withpiracetam,and treatment group was treated with acorus gramineus.Before and after treatment,the clinical symptoms and vital signs of two groups were observed,intelligence was evaluated with Hasegawa dementia scale revised（HDS-R）,and curative effect and adverse drug reactions were observed. Results After one course of treatment,HDS-R results of two groups were improved,the differences were statistically significant（t=0.619,0.506,P〈0.05）.After treatment HDS-R results of the treatment group were significantly higher than the control group（t=0.425,P〈0.05）.After treatment efficiency of treatment group was 57.4%,the total effective rate was 90.7%,were significantly higher than those of the control group（χ^2=12.421,5.146,P〈0.05）.The incidence of adverse drug reaction of treatment group was 9.3%（5/54）,the incidence of adverse drug reaction of control group was 8.0%（4/50）,there was no statistically significant difference（χ^2=1.316,P〉0.05）. Conclusion Acorus gramineus can improve the intellect of patients with cerebral vascular dementia,and the therapy has a high clinical value.