Raphanus sativus L. var niger as a source of Phytochemicals for the Prevention of Cholesterol Gallstones |
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| Authors: | Ibrahim Guillermo Castro‐Torres Minarda De la O‐Arciniega Janeth Gallegos‐Estudillo Elia Brosla Naranjo‐Rodríguez Miguel Ángel Domínguez‐Ortíz |
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| Affiliation: | 1. Instituto de Química, Universidad Nacional Autónoma de México, , México, D.F., México;2. área Académica de Farmacia, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, , Pachuca de Soto, Hidalgo, México;3. Laboratorio de Productos Naturales, Instituto de Ciencias Básicas, Universidad Veracruzana, , Xalapa de Enríquez, Veracruz, México;4. Laboratorio de Neurofarmacología, Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, , México, D.F., México |
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| Abstract: | Raphanus sativus L. var niger (black radish) is a plant of the cruciferous family with important ethnobotanical uses for the treatment of gallstones in Mexican traditional medicine. It has been established that the juice of black radish decreases cholesterol levels in plasma and dissolves gallstones in mice. Glucosinolates, the main secondary metabolites of black radish, can hydrolyze into its respective isothiocyanates and have already demonstrated antioxidant properties as well as their ability to diminish hepatic cholesterol levels; such therapeutic effects can prevent the formation of cholesterol gallstones. This disease is considered a current problem of public health. In the present review, we analyze and discuss the therapeutic effects of the main glucosinolates of black radish, as well as the effects that this plant has on cholesterol gallstones disease. Copyright © 2013 John Wiley & Sons, Ltd. |
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| Keywords: | Raphanus sativus L. var niger gallstones glucosinolates cholesterol |
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