补肾益脑汤治疗血管性痴呆临床研究

目的：探讨补肾益脑汤治疗血管性痴呆的临床疗效。方法：将96例血管性痴呆患者随机分为治疗组与对照组，对照组46倒采用比拉西坦注射液、银杏叶注射液，静脉滴注。治疗组50例在对照组基础上服用补肾益脑汤（方药组成：熟地黄15g，枸杞子15g，白芍20g，山茱萸15g，巴戟天8g，肉苁蓉15g，党参20g，白术20g，山药30g，茯苓15g，杜仲15g，益智仁20g，石菖蒲30g，郁金15g，远志12g，怀牛膝15g）治疗，观察两组临床疗效。结果：两组均能改善患者的MMSE评分，治疗组优于对照组，差异有统计学意义（P〈0．05）。治疗组症候改善明显，与对照组比较，差异有统计学意义（P〈0．05）。结论：补肾益脑汤治疗血管性痴呆疗效显著。

Clinical Research on Serf-formulated Yishen Bunao Decoction for the Treatment of Vascular Dementia

Objective：To investigate the clinical therapeutic effects of self-formulated Yishen Bunao Decoction for the treatment of vascular dementia. Methods：96 cases of vascular dementia patients were randomly divided into the treatment group and control group. The control group with 46 cases was given intravenous infusion of Piracetam injection and ginkgo leaf injection,while the treatment group of 50 patients, based on the above treatment was administered self-formulated Yishen Bunao Decoction（ Recipe components：Rehmannia 15 g, medlar 15 g, white peony root 20 g, dogwood 15 g, Morinda 8 g, Cistanche 15 g, Radix Codonopsis 20 g, Atractylodes 20 g, Chinese yam 30 g,Poria 15 g,Eucommia 15 g,bitter cardamon 20 g,grassleaved sweetflag rhizome 30 g,turmeric 15 g,the Polygalaceae 12 g,radix achyranthis bidentatae 15 g）. The clinical therapeutic effects of both groups were observed. Resuhs：Both groups could improve the MMSE scores of patients and the treatment group was superior to the control group. The treatment group could significant improve the symptoms and had comparability（P 〈 0.01 ）. Conclusion：Yishen Bunao Decoction has significant therapeutic effect for the treatment of vascular dementia.