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艾滋病患者带状疱疹反复发作的机制探讨
引用本文:郭会军,付涵.艾滋病患者带状疱疹反复发作的机制探讨[J].河南中医药学刊,2012(6):653-654.
作者姓名:郭会军  付涵
作者单位:[1]河南中医学院第一附属医院,河南郑州450000 [2]河南中医学院,河南郑州450008
基金项目:国家“十一五”重大科技专项(编号:2008ZXl0005-003)
摘    要:目的:探讨艾滋病患者多次复发带状疱疹的机制。方法:结合临床观察,总结分析近年来国内外学者关于艾滋病患者多次复发带状疱疹机制的科研成果。结果:由水痘-带状疱疹病毒(VZV)引起的带状疱疹患者的T淋巴细胞亚群(CD3+、CD4+、CD8+)以及CD4+/CD8+比值与正常人比较均降低,其中T辅助细胞(CD4+)明显下降,T辅助细胞与T抑制细胞的比值(CD4+/CD8+)明显降低。结论:艾滋病患者易发生带状疱疹与免疫力低下有关。

关 键 词:艾滋病  人类免疫缺陷病毒  水痘-带状疱疹病毒  病毒特性  T淋巴细胞  免疫分子  基因表达

Exploration on the Mechanism of Recurrent Herpes Zoster in Patients with AIDS
Guo Huijun,FU Han.Exploration on the Mechanism of Recurrent Herpes Zoster in Patients with AIDS[J].Journal of Henan college of Traditional Chinese Medicine,2012(6):653-654.
Authors:Guo Huijun  FU Han
Institution:1.The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China 450000; Henan University of Traditional Chinese Medicine, Zhengzhou, Henan, China 450008)
Abstract:Objective : To investigate the mechanisms of muhiple recurrent herpes zoster in AIDS patients. Methods : Scientific research achievements made by the domestic and foreign scholars in recent years in the mechanism of multiple recurrent herpes zoster in AIDS patients were summarized and analyzed combined with clinical observations. Results: Compared with the normal people, T-lymphocyte subsets(CD3 + , CD4 + , CDs + ) and CD4 +/CD8+ ratio of the patients with herpes zoster caused by VZV decreased, amone which T- helper cells decreased significantly and the ration of T helper cells and T suppressor cell( CD4 +/CD8+ ) decreased significantly. Conclusion: The suscepatibility of AIDS patients to get herpes zoster are related with hypoimmunity.
Keywords:AIDS  HIV  VZV  virus characteristics  T lymphocytes  immune molecule  gene expression
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