益气散结消水汤治疗肝硬变腹水临床研究

目的：探讨益气散结消水汤治疗肝硬变腹水临床疗效。方法：选择100例患者随机分为两组，治疗组60例，对照组40例。两组均予西药保肝、支持疗法，治疗组在此基础上加服中药益气散结消水汤（药物组成：人参12g，黄芪30g，白茯苓30g，炒白术30g，丹参30g，郁金12g，川芎12g，赤芍15g，云苓皮30g，猪苓30g，泽泻30g，车前子30g，白茅根30g，大腹皮30g，炙鳖甲30g，炮穿山甲9g，厚朴15g，枳实15g，细辛3g，沉香（冲）3g，炒麦芽30g，茵陈40g）治疗。结果：治疗组有效率为83．3％，对照组有效率为60．0％，两组比较，差异统有计学意义（P〈0．01）。两组腹水消退时间、肝脏功能（做l、ALT、Alb）、腹水消退后疗效巩固比较及两组治疗前后腹围、体质量变化比较，治疗组均显著优于对照组（P〈0．01，P〈0．05，P〈0．01）。结论：益气散结消水汤结合西药治疗肝硬变腹水在保护肝脏功能，促进腹水消退，降低腹水复发，提高生活质量等方面效果较单用西药为佳。

Clinical Study on the Treatment of Ascites Due to Cirrhosis by Yiqi Xiaoshui Decoction

Objective：To observe the clinical curative effects of Yiqi Sanjie Xiaoshui Decoction on the treatment of 60 Cases of ascites due to cirrhosis. Methods： 100 patients were randomly divided into two groups,the treatment group of 60 eases and the control group of 40 cases. Both groups were given western medicine of hepatoproteetive treatment and supportive therapy. Based on the above treatment, the treatment group was added traditional Chinese medicine Yiqi Sanjie Xiaoshui Decoction （ drug composition：white ginseng 12 g,Salvia Astragalus 30 g,Poria Cocos 30 g,fried Atractylodes 30 g,radix salviae miltiorrhizae 30 g,turmericl2 g,hemlock parsley 12 g,red peony root 15 g,Poria from Yunnan of China 30 g,Polyporus 30 g,cloud Ling skin Alisma 30g Plantago 30 g,Rhizoma Imperatae 30 g, shell of areca nut 30 g,Sunburn turtle 30 g,cannon Shanjia 9 g,Magnolia 15 g,fried malt Citrus aurantium 15 g,asarum 3 g,agilawood 3 g,fried germinated barley 30 g, Herba Artemisiae CapiUaris 40 g）. Results：The effective rate of the treatment group was 83.3 % and the rate of the control group was 60%. Comparison of the two groups showed the difference was statistically significant（P 〉0.01 ）. The comparions between two groups showed that the treatment group was significantly better than the control group in the following aspects, regression time of ascites,liver function （Tbil, ALT and Alb）, efficacy consolidation after the disappearance of ascites, abdominal circumference and weight change before and after treatment（P 〈0.01 ,P 〈0.05 ,P 〈0.01 ）. Conclusion：The use of self-formulated Chinese medicine decoction combined with western medicine for the treatment of ascites due to cirrhosis is superior to the single use of western medicine in protecting liver function, promoting the regression of ascites, reducing recurrence of ascites and improving quality of life and other aspects.