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更年期综合征动物模型的特点及研究展望
引用本文:李瑞奇,白明,苗明三.更年期综合征动物模型的特点及研究展望[J].河南中医药学刊,2012(6):708-710.
作者姓名:李瑞奇  白明  苗明三
作者单位:河南中医学院,河南郑州450008
基金项目:郑州市科技领军人才项目(编号:0910SGYS3527);河南省国际合作项目(编号:112102310076)
摘    要:目的:探讨更年期综合征动物模型的特点及发展方向。方法:分析和归纳现有更年期综合征动物模型的优势及不足,提出完善现有更年期综合征动物模型的思路和方法。结果:建立体现病证结合的更年期综合征动物模型和模型评价指标体系,并进行反治验证,有利于对更年期综合征的研究。结论:病证结合方法是完善更年期综合征模型的重要途径。

关 键 词:更年期综合征  动物模型  卵巢摘除  病证结合模型  病因模型  模型评价指标

Characteristics and Prospect of Animal Models of Menopause Syndrome
Li Ruiqi,Bai Ming,Miao Mingsan.Characteristics and Prospect of Animal Models of Menopause Syndrome[J].Journal of Henan college of Traditional Chinese Medicine,2012(6):708-710.
Authors:Li Ruiqi  Bai Ming  Miao Mingsan
Institution:(Henan University of Traditional Chinese Medicine,Zhengzhou, Henan, China 450008)
Abstract:Objective:To explore the characteristics and development direction of animal model of menopausal syndrome. Methods:The advantages and disadvantages of the existing animal models of menopause syndrome were analyzed and summarized to propose ideas and methods to improve the existing animal models of menopause syndrome. Results : The animal models of menopause syndrome which were closer to clinic and reflected the combination of disease and syndrome were build and system of model assessment index was established to verify,which faciliated the research on menopause syndrome. Conclusion:The establishment of model with a combination of disease and syndrome is an important way to improve models of menopausal syndrome.
Keywords:menopause syndrome  animal models  ovariectomy  model with a combination of disease and syndrome  model of etiology  model assessment index
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