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| 脂必妥对大鼠实验性高脂血症的作用 | |
| 引用本文： | 吕萍,陈海峰,谭青霜,徐康森. 脂必妥对大鼠实验性高脂血症的作用[J]. 中国生化药物杂志, 2007, 28(4): 275-276 |
| 作者姓名： | 吕萍 陈海峰 谭青霜 徐康森 |
| 作者单位： | 1. 中国药品生物制品检定所,北京,100050 2. 国家药品审评中心,北京,100038 3. 山东畜牧兽医职业学院,山东,潍坊,261061 |
| 摘 要： | 目的研究脂必妥对大鼠实验性高脂血症的调血脂作用。方法采用喂养法建立动物模型,给予不同剂量的脂必妥,4周后取血测定血脂含量。结果脂必妥可明显降低血清总胆固醇和甘油三酯的水平,显著提高血清高密度脂蛋白胆固醇。结论脂必妥对大鼠实验性高脂血症有明显的调血脂作用。 |
| 关 键 词： | 脂必妥 高脂血症 调血脂作用 |
| 文章编号： | 1005-1678（2007）04-0275-02 |
| 收稿时间： | 2006-10-30 |
| 修稿时间： | 2006-10-302006-12-22 |
Effect of Zhibituo on blood lipid in hyperlipidemia rats |
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| LU Ping,CHEN Hai-feng,TAN Qing-shuang,XU Kang-sen. Effect of Zhibituo on blood lipid in hyperlipidemia rats[J]. Chinese Journal of Biochemical Pharmaceutics, 2007, 28(4): 275-276 | |
| Authors: | LU Ping CHEN Hai-feng TAN Qing-shuang XU Kang-sen |
| Affiliation: | 1. National Institute for the Control of Pharmaceutical and Biological Products, Beijing 100050, China; 2. Center for Drug Evaluation, Beijing 100038, China ; 3. Shandong Vocational Animal Science and Veterinary Colleage , Weifang 261061, China |
| Abstract: | Purpose To study the effect of Zhibituo on serum lipid in experimental hyperlipidemia rats. Methods Hyperlipidemia rat model was made by feeding high fat emulsion and treated with different doses of Zhibituo. After 4 weeks, blood lipids were measured respectively. Results Zhibituo could decrease the serum total cholesterol and triglyceride concentration, as well as increase the serum high density lipoprotein cholesterol. Conclusion Zhibituo was effective in modulating the serum lipids in hyperlipidemia rats. |
| Keywords: | Zhibituo hyperlipidemia lipid-lowering effect |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |