破裂颅内微小动脉瘤的血管内栓塞技术探讨

目的 评估血管内栓塞破裂颅内微小动脉瘤的疗效和安全,探讨其技术要点.方法 回顾性分析2007年1月至2010年11月郑州大学第一附属医院22例微小动脉瘤破裂所致的蛛网膜下腔出血患者的临床、影像学结果和术中操作.22例患者中,男13例,女9例;平均年龄54.5岁.Hunt-Hess分级:Ⅰ～Ⅱ级和Ⅲ～Ⅳ级的患者分别为12和10例.22个动脉瘤根据位置分类:前交通动脉、大脑中动脉、后交通动脉和颈内动脉动脉瘤分别为7、2、8和5个.所有患者均采用弹簧圈栓塞治疗(其中7例支架辅助,2例球囊辅助).结果 22个动脉瘤中,致密栓塞17例,瘤颈残留1例,瘤腔残留4例,未出现弹簧圈移位和载瘤动脉血栓栓塞事件,术中出现动脉瘤破裂出血2例,术后一过性轻偏瘫1例,死亡1例.结论 血管内栓塞破裂颅内微小动脉瘤效果可靠;规范且熟练的操作、手术方式和血管内材料的合适选择是微小动脉瘤治疗成败的关键.

Abstract：

Objective To explore the technique of endovascular therapy for ruptured intracranial very small aneurysms and evaluate the feasibility and safety of endovascular treatment of such aneurysms. Methods Twenty-two intracranial very small aneurysms in 22 patients with subarachnoid hemorrhage undergoing endovascular therapy were reviewed retrospectively. Their clinical, imaging,interventional and follow-up data were analyzed. Among them, there were 13 males and 9 females with a mean age of 54. 5 years old. The Hunt-Hess grade was as follows:Grades Ⅰ and Ⅱ ( n = 12) and Grades Ⅲ and Ⅳ (n = 10). The locations of aneurysms were as follows: anterior communicating artery (n = 7),middle cerebral artery ( n = 2), posterior communicating artery ( n = 8 ) and internal carotid artery ( n = 5 ).All aneurysms were embolized with coils. Among them, 7 received stent assistance and 2 balloon remodeling. Results Among 22 coiled aneurysms, complete occlusion was achieved in 17 aneurysms, neck remnant occurred in 1 patient and aneurysm remnant in 4 patients. Two aneurysms ruptured during coiling and one patient died from it. One patient had transient hemiparesis. All patients received a follow-up of 3 -36months and there was no recurrent hemorrhage. Conclusion Endovascular treatment of ruptured intracranial very small aneurysms seems to be technically feasible, relatively safe and practically effective. An appropriate selection of interventional materials and use of sophisticated techniques yield an excellent outcome.

Endovascular treatment of ruptured intracranial very small aneurysms

Objective To explore the technique of endovascular therapy for ruptured intracranial very small aneurysms and evaluate the feasibility and safety of endovascular treatment of such aneurysms. Methods Twenty-two intracranial very small aneurysms in 22 patients with subarachnoid hemorrhage undergoing endovascular therapy were reviewed retrospectively. Their clinical, imaging,interventional and follow-up data were analyzed. Among them, there were 13 males and 9 females with a mean age of 54. 5 years old. The Hunt-Hess grade was as follows:Grades Ⅰ and Ⅱ ( n = 12) and Grades Ⅲ and Ⅳ (n = 10). The locations of aneurysms were as follows: anterior communicating artery (n = 7),middle cerebral artery ( n = 2), posterior communicating artery ( n = 8 ) and internal carotid artery ( n = 5 ).All aneurysms were embolized with coils. Among them, 7 received stent assistance and 2 balloon remodeling. Results Among 22 coiled aneurysms, complete occlusion was achieved in 17 aneurysms, neck remnant occurred in 1 patient and aneurysm remnant in 4 patients. Two aneurysms ruptured during coiling and one patient died from it. One patient had transient hemiparesis. All patients received a follow-up of 3 -36months and there was no recurrent hemorrhage. Conclusion Endovascular treatment of ruptured intracranial very small aneurysms seems to be technically feasible, relatively safe and practically effective. An appropriate selection of interventional materials and use of sophisticated techniques yield an excellent outcome.