Ⅱ型糖尿病患者血清中超氧化物歧化酶含量变化的临床实验观察 |
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引用本文: | 唐国全. Ⅱ型糖尿病患者血清中超氧化物歧化酶含量变化的临床实验观察[J]. 广西医学, 2003, 25(5): 687-688 |
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作者姓名: | 唐国全 |
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作者单位: | 广西壮族自治区人民医院检验科,530021 |
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摘 要: | 目的 :探讨超氧化物歧化酶 (SOD)在Ⅱ型糖尿病 (NIDDM)患者血清中的变化。方法 :采用黄嘌呤氧化酶法测定血清中SOD的水平。结果 :(1)NIDDM组血清总SOD(TSOD)与对照组比较含量无明显差别 (P >0 0 5 ) ,MnSOD及CuZnSOD与对照组比较分别高于和低于正常对照组 (P <0 0 1)。 (2 )男女二组的性别比较差异无显著性 (P >0 0 5 )。结论 :检测血清中SOD对预测NIDDM患者血管并发症的发生、发展有重要意义
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关 键 词: | Ⅱ型糖尿病 血液检验 超氧化物歧化酶 黄嘌呤氧化酶法 |
Clinical and experimental observation on the change of SOD contant in serum of patientswith non insulin dependent diabetes mellitus |
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Affiliation: | Nanning 530021 |
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Abstract: | Objective:To evaluate the change of superoxide dismutase(SOD) in patients with non insulin dependent diabetes millitus(NIDDM).Methods:SOD content in serum was determined with xanthine oxidase.Results:1.There was not significant difference in serum levels of total SOD(TSOD) between NIDDM group and control group(P>0 05).However,Mn SOD in NIDDM group were higher than that in control group,and CuZn SOD in NIDDM group were lower than that in control group,respectively(P<0 01).2.There was not significant difference between male and female.Conclusions:To determine the SOD content in serum of patients with NIDDM has great significance for predicting occurrence and development of complication as vascular disease. |
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Keywords: | Non insulin dependent diabetes mellitus Superoxide dismutase |
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