| 慢性乙型肝炎患者DC-SIGN启动区变异分析 |
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| 作者姓名： | Chen L Li C Meng X Zhu P Tan D |
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| 作者单位： | 中南大学湘雅医院感染科, 长沙 410008 |
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| 基金项目： | supported by the Natural Science Foundation of Hunan Province,P.R.China(07JJ5021) |
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| 摘 要： | 目的:了解慢性乙型肝炎(chronic hepatitis B,CHB)患者与既往乙型肝炎病毒(hepatitis B virus,HBV)感染者体内树突状细胞特异性细胞间黏附分子-3结合非整合素因子(dendritic cell-specific intercellular adhension molecule-3-...
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| 关 键 词： | DC-SIGN 乙型肝炎病毒 乙型肝炎 慢性 启动区 突变 |
Mutation analysis of DC-SIGN promoter in chronic hepatitis B patients |
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| Chen L,Li C,Meng X,Zhu P,Tan D.Mutation analysis of DC-SIGN promoter in chronic hepatitis B patients[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),2011,36(11):1052-1058. |
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| Authors: | Chen Li Li Congzhi Meng Xiujuan Zhu Ping'an Tan Deming |
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| Institution: | Department of Infectious Diseases, Xiangya Hospital, Central South University, Changsha 410008, China |
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| Abstract: | Objective To investigate whether there is mutation in DC-SIGN promoter region in patients with chronic hepatitis B(CHB) and healthy persons previously infected with hepatitis B virus(HBV) and to explore the relationship between the mutation in dendritic cell-specific intercellular adhension molecule-3-grabbing nonintegrin(DC-SIGN) promoter region and HBV.Methods The studied population was composed of two cohorts: 47 CHB patients and 20 healthy persons previously infected with HBV.The mutation in DC-SIGN pro... |
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| Keywords: | DC-SIGN hepatitis B virus hepatitis B chronic promoter region mutation |
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