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异基因造血干细胞移植治疗恶性血液病104例临床分析
引用本文:Chen Y,Xu Y,Zhu Y,Fu G,Liu Y,Peng J,Fu B,He Q,Wu D,Li X,Zhao X,Chen F. 异基因造血干细胞移植治疗恶性血液病104例临床分析[J]. 中南大学学报(医学版), 2011, 36(9): 859-864. DOI: 10.3969/j.issn.1672-7347.2011.09.008
作者姓名:Chen Y  Xu Y  Zhu Y  Fu G  Liu Y  Peng J  Fu B  He Q  Wu D  Li X  Zhao X  Chen F
作者单位:中南大学湘雅医院血液科, 长沙 410008
摘    要:目的:评价异基因造血干细胞移植治疗恶性血液病的疗效.方法:对1999年12月至2010年1月间在湘雅医院接受异基因造血干细胞移植(allo-HSCT)的104例恶性血液病患者进行回顾性分析.采用Kaplan-Meier法计算移植后患者移植相关死亡率(TRM)、复发率(RR)、5年总生存率(OS)及5年无病生存率(DFS...

关 键 词:异基因造血干细胞移植  恶性血液病  无病生存率  急性移植物抗宿主病

Clinical analysis of 104 patients with hematological malignancy after allogeneic hemotopoietic stem cell transplantation
Chen Yan,Xu Yajing,Zhu Yan,Fu Gan,Liu Yi,Peng Jie,Fu Bin,He Qun,Wu Dengshu,Li Xiaolin,Zhao Xielan,Chen Fangping. Clinical analysis of 104 patients with hematological malignancy after allogeneic hemotopoietic stem cell transplantation[J]. Journal of Central South University. Medical sciences, 2011, 36(9): 859-864. DOI: 10.3969/j.issn.1672-7347.2011.09.008
Authors:Chen Yan  Xu Yajing  Zhu Yan  Fu Gan  Liu Yi  Peng Jie  Fu Bin  He Qun  Wu Dengshu  Li Xiaolin  Zhao Xielan  Chen Fangping
Affiliation:Department of Hematology, Xiangya Hospital, Central South University, Changsha 410008, China
Abstract:Objective To study the efficacy of allogeneic hemotopoietic stem cell transplantation(allo-HSCT) for hematological malignancy. Methods A total of 104 patients with hematological malignancy,who underwent allo-HSCT in Xiangya Hospital from December 1999 to January 2010,were retrospectively analyzed.Of the patients,the transplantation related mortality(TRM),relapse rate(RR),5-year overall survival(OS) and disease free survival(DFS) were estimated by Kaplan-Meier analysis.The unfavorable prognostic factors were...
Keywords:allogeneic hemopoietic stem cell transplantation  hematological malignancy  disease free survival  aGVHD  
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