宫颈癌筛查系统不同点探区间在宫颈癌筛查中的应用价值

目的:评价宫颈癌筛查系统不同点探区间在宫颈癌筛查中的应用价值.方法:取液基薄层细胞检测(TCT)为不典型鳞状细胞(ASCUS)及以上病例50例,用宫颈癌筛查系统进行15～20点、21～32点及2种不同点数的联合检测,再与宫颈活检病理学结果阳性病例进行对比研究.结果:病理学检测结果异常者21例,其中子宫颈上皮内瘤变(CI...

Value of different target area in TruScreen system for the screening of cervical cancer

Objective： To evaluate the value of different target area in TruScreen system for the screening of cervical cancer.Methods： A total of 50 cases that were confirmed as ASCUS or above according to TCT were enrolled in this study.And diagnosis results of detecting 15-20 points,21-32 points,or the combination of the two were compared with pathological detection results to evaluate their accuracy.Results： 21 cases of pathological detection revealed abnormal results in 21 cases,of which 10 were CINⅠ,6 were CINⅡ,and 4 were CINⅢ,1 case was invasive carcinoma.Detection of 15-20 points with truescan system showed positive rate of 56%（28/50）,with a sensitivity of 76.19%（16/21）and specificity of 58.62%（17/29）.Detection of 21-32 points showed positive rate of 70%（35/50） showing sensitivity of 90.48%（19/21） and the specificity of 44.83%（13/29）.Combined detection of the two areas showed positive rate of 48%（24/50）.Excluding 20 cases with different results according to the two detecting methods,there were 8 false negative cases,showing sensitivity of 84.62%（11/13）,specificity of 35.29%（6/17）,and the rate of unanimous results was 66%,64% and 56.67%,respectively（P0.01）.Conclusions： The TruSystem shows great diagnosis accuracy according to pathological detection.Abnormal results of both detecting areas indicate high degree of lesions.