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多囊卵巢综合征患者胰岛素抵抗和氧化应激的关系
引用本文:李根霞,李巍巍.多囊卵巢综合征患者胰岛素抵抗和氧化应激的关系[J].郑州大学学报(医学版),2011,46(5):759-762.
作者姓名:李根霞  李巍巍
作者单位:1. 郑州大学第三附属医院妇产科 郑州450052
2. 郑州大学第三附属医院生殖中心 郑州450052
摘    要:目的:探讨多囊卵巢综合征(PCOS)患者胰岛素抵抗(IR)状态与氧化应激的关系.方法:PCOS患者80例,包括IR组患者43例和非IR组患者37例,另取因输卵管或男性原因不育而月经规律、内分泌激素正常的对照组患者30例,检测各组患者空腹血糖( FSG)、空腹胰岛素(FINS),计算胰岛素抵抗指数(HOMA-IR)并检验...

关 键 词:多囊卵巢综合征  胰岛素抵抗  氧化应激

Relationship between insulin resistance and oxidative stress in patients with PCOS
LI Genxia,LI Weiwei.Relationship between insulin resistance and oxidative stress in patients with PCOS[J].Journal of Zhengzhou University: Med Sci,2011,46(5):759-762.
Authors:LI Genxia  LI Weiwei
Institution:LI Genxia1),LI Weiwei2)1)Department of Gynecology and Obstetrics,the Third Affiliated Hospital,Zhengzhou University,Zhengzhou 450052 2)Center of Reproductive Medicine,Zhengzhou 450052
Abstract:Aim:To investigate the relationship between insulin resistance(IR)and oxidative stress in patients with polycystic ovary syndrome(PCOS).Methods:The concentration levels of serum malondialdehyde(MDA),serum glutathione peroxidase(GSH-Px)and the activity of serum superoxide dismutase(SOD)in 80 women with PCOS(43 associated with IR and 37 without IR),and 30 normal women were measured.Results:The levels of serum GSH-Px,SOD,and MDA among 3 groups had significant differences(F=12.203,27.221,and 16.715,P<0.001).Com...
Keywords:polycystic ovary syndrome  insulin resistance  oxidative stress  
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