| 抵抗素在大鼠重症急性胰腺炎的表达及意义 |
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| 引用本文： | 张惠淑,李明江,郭少军,张国良,林群,严斌.抵抗素在大鼠重症急性胰腺炎的表达及意义[J].海南医学院学报,2011,17(8):1028-1031. |
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| 作者姓名： | 张惠淑 李明江 郭少军 张国良 林群 严斌 |
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| 作者单位： | 深圳市坪山新区人民医院,广东深圳,518118 |
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| 基金项目： | 广东省深圳市卫生科技计划项目(201003480)~~ |
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| 摘 要： | 目的:检测抵抗素在大鼠重症急性胰腺炎的表达情况,分析抵抗素在重症急性胰腺炎中的意义.方法:将45只雄性SD大鼠分为正常对照组(n=5)、假手术组(n=20)和模型组(n=20),用胰管注射牛磺胆酸钠的办法制作重症胰腺炎模型;用双抗体夹心ABC-ELISA方法检测血清抵抗素、白介素-6(IL-6)和C反应蛋白(CRP);...
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| 关 键 词： | 重症急性胰腺炎 抵抗素 IL-6 CRP |
Expression and significance of resistin in rats of severe acute pancreatitis |
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| ZHANG Hui-shu,LI Ming-jiang,GUO Shao-jun,ZHANG Guo-liang,LIN Qun,YAN Bin.Expression and significance of resistin in rats of severe acute pancreatitis[J].Journal of Hainan Medical College,2011,17(8):1028-1031. |
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| Authors: | ZHANG Hui-shu LI Ming-jiang GUO Shao-jun ZHANG Guo-liang LIN Qun YAN Bin |
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| Institution: | (People′s Hospital in New Pingshan District,Shenzhen 518118,China) |
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| Abstract: | Objective: To investigate the expression and significance of resistin in rats of severe acute pancreatitis.Methods: A total of 45 male Sprague Dawley rats were randomly divided into three groups: control group(n=5),sham operation group(n=20),and SAP group(n=20).Severe acute pancreatitis model was induced by injection of sodium taurocholate into the pancreatobiliary duct.Double antibody sandwich ABC-ELISA method was performed to determine the expression of resistin,interleukin-6(IL-6) and C-reactive protein(... |
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| Keywords: | Severe acute pancreatitis Resistin Interleukin-6 C-reactive protein |
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