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Axillary lymph node metastasis following resection of abdominal wall laparoscopic port site recurrence of gallbladder cancer
Authors:Povoski Stephen P  Ouellette James R  Chang William W L  Jarnagin William R
Affiliation:(1) Division of Surgical Oncology, Department of Surgery, The Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, The Ohio State University, N-924 Doan Hall, 410 West 10th Avenue, Columbus, OH 43210-1228, USA;(2) Division of Hepatobiliary Surgery of the Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA;(3) Department of Pathology, Robert C. Byrd Health Science Center and Mary Babb Randolph Cancer Center of West Virginia University, Morgantown, WV, USA;(4) Department of Surgery, Robert C. Byrd Health Science Center and Mary Babb Randolph Cancer Center of West Virginia University, Morgantown, WV, USA
Abstract:Abdominal wall port site recurrence of gallbladder cancer is well described in the literature in patients that have undergone laparoscopic cholecystectomy with the incidental finding of a gallbladder cancer. The etiology and consequences of this type of metastatic recurrence are unclear. This report describes two cases with the unique sequelae of the interval development of nodal metastases to the axillary lymph nodes following resection of an abdominal wall laparoscopic port site recurrence of gallbladder cancer. The first case involves a patient who developed an isolated left axillary lymph node metastasis approximately 10 months after undergoing resection of a left-sided abdominal wall port site recurrence for a T2 gallbladder cancer. The original tumor had been found at laparoscopic cholecystectomy and definitively treated surgically approximately 3 years earlier. The second case involves a patient who developed isolated nodal metastases to the right axillary lymph nodes approximately 4 months after undergoing resection of right-sided abdominal wall port site recurrence, segment 4/5 hepatic resection, and portal lymphadenectomy for a T2 gallbladder cancer. This tumor had originally been found at laparoscopic cholecystectomy approximately 1 year earlier. These unique sequelae of the interval development of nodal metastases to the axillary lymph nodes demonstrated in both cases has not been previously reported.
Keywords:Gallbladder cancer  Port site recurrence  Axilla  Lymph node metastasis
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