急性脑梗死68例超敏C反应蛋白检测及意义

目的探讨急性脑梗死血清超敏C反应蛋白（hs-CRP）水平的变化及其临床意义。方法测定68例急性脑梗死的血清hs-CRP含量,并与60例健康体检者作比较。结果治疗1d、7d后脑梗死组血清hs-CRP水平分别为6.7±2.2和6.56±5.4,明显高于正常对照组,差异有统计学意义（P〈0.01）。治疗3个月后两组血清hs-CRP水平差异无统计学意义（P〉0.05）。结论 hs-CRP能够更灵敏地反应炎症情况,为临床评价脑梗死病情变化提供有意义的参考指标。

Detection and significance of hs-CRP levels in acute cerebral infarction patients

Objective To detect the high-sensitive C-reactive protein（hs-CRP） from acute cerebral infarction patients and analyze its clinical significance.Methods The concentrations of hs-CRP in 68 acute cerebral infarction patients and 60 healthy controls were detected and compared.Results The concentrations of hs-CRP in serum of acute cerebral infarction patients one day and three days after treatment were 6.7±2.2 and 6.56±5.4,significantly higher than that of the controls,showing significant differences（P0.01）.The hs-CRP levels in both groups were not significantly different three months after treatment（P0.01）.Conclusion The hs-CRP is a sensitive indicator in reflecting of inflammatory conditions of acute cerebral infarction patients and it also offer reference for clinical assessment of variations and severity of the diseasae.