159株阴沟肠杆菌的临床分布及耐药性分析

目的分析和探讨2007～2009年阴沟肠杆菌的临床分布及耐药情况,以指导临床合理用药,防止耐药菌株的产生及传播。方法 2007～2009年住院患者标本中分离的159株阴沟肠杆菌,VITEK-32自动微生物鉴定及药敏分析系统鉴定菌种并药敏试验,对阴沟肠杆菌的分布状况及药敏结果行分析。结果 159株阴沟肠杆菌主要分布在痰液及伤口分泌物;阴沟肠杆菌对青霉素、第一、二代头孢菌素高度耐药（〉80%）,对第三、四代头孢菌素及喹诺酮类抗菌素耐药率逐年上升,对碳青霉烯类、氨基糖苷类低度耐药。结论阴沟肠杆菌的临床检出率和耐药率日趋严重,应加强耐药性监测,指导临床合理使用抗菌药物,控制阴沟肠杆菌引起的医院感染。

Clinical distribution and drug resistance of 159 Enterobacter cloacae strains

Objective To survey the clinical distribution and drug resistance of 159 Enterobacter cloacae strains Methods During 2007~2009,159 clinical strains of Enterobacter cloacae were isolated from the patients and the clinical distribution and drug resistance were surveyed.Results The 159 clinical Enterobacter cloacae strains were isolated from the sputum and wound secretion.The clinical strains of Enterobacter cloacae were high resistant to the penicillin G,followed by the second generation cephalosporin;the res...