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630例药品不良反应调查分析
引用本文:刘日升,张雯.630例药品不良反应调查分析[J].中国热带医学,2011,11(9):1154-1155,1160.
作者姓名:刘日升  张雯
作者单位:海南医学院附属医院,海南海口,570102
摘    要:目的了解医院药品不良反应(ADR)发生的情况及特点,为临床合理用药及药物安全性评价提供参考。方法对2008~2010年收集的630例不良反应报告表,分别从患者年龄、给药途径、药品种类、抗微生物药物类别、累及的器官或系统及临床表现等方面进行统计分析。结果 ADR多发生在大于60岁年龄组(23.81%);静脉滴注导致的ADR发生率最高,占71.59%;ADR发生率最高的为抗微生物药物,为62.54%,其中头孢菌素类药物最多,占118例;ADR的临床表现以皮肤及其附件损害最为常见,占44.76%。结论引起ADR的因素有多方面,应加强ADR监测,促进临床合理用药,减少ADR的发生。

关 键 词:药品不良反应  报告  分析  合理用药

Clinical analysis of adverse drug reactions occurred to 630 cases from 2008 to 2010
LIU Ri-sheng,ZHANG Wen.Clinical analysis of adverse drug reactions occurred to 630 cases from 2008 to 2010[J].China Tropical Medicine,2011,11(9):1154-1155,1160.
Authors:LIU Ri-sheng  ZHANG Wen
Institution:LIU Ri-sheng,ZHANG Wen.(The Affiliated Hospital of Hainan Medical College,Haikou 570102,Hainan,P.R.China)
Abstract:Objective To analyze the clinical features of adverse drug reactions(ADR) occurred to 630 cases and provide reference for rational use of drugs in the clinical treatment.Methods The route of administration,drug category,anti-microbial drug classification,ADR-involved organs or systems and clinical manifestations,etc.of 630 ADR cases collected from 2008 to 2010 were analyzed statistically.Results Patients over the age of 60 years showed the highest incidence(23.81%).Most of ADR cases were induced by intraven...
Keywords:Adverse drug reactions  Report  Analysis  Rational use of drugs  
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