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两种梅毒螺旋体血清学检测方法的临床应用评价
引用本文:陈美琚,王欣欣,张忠英. 两种梅毒螺旋体血清学检测方法的临床应用评价[J]. 中国热带医学, 2011, 11(9): 1143-1144
作者姓名:陈美琚  王欣欣  张忠英
作者单位:厦门大学附属中山医院临检中心,福建厦门,361005
摘    要:目的探讨TRUST和TPPA联合检测对梅毒的监控和诊治价值,为临床诊治梅毒提供实验依据。方法采用TRUST法和TPPA法测定2 083例血清标本(其中910例梅毒患者血清)。结果对910例梅毒患者血清检测,TRUST法检出773例阳性,敏感性为84.9%,特异性为96.1%。TPPA法检出899例阳性,敏感性为98.7%,差异有统计学意义(P〈0.05);TPPA法具有很高的特异性和灵敏度。结论 TRUST和TPPA联合检测为临床诊治梅毒提供更有价值的实验依据,更有利于梅毒的监控和诊治。

关 键 词:梅毒  TRUST  TPPA  联合检测

Clinical evaluation of two serological methods for detecting Treponema pallidum
CHEN Mei-jun,WANG Xin-xin,ZHANG Zhong-ying. Clinical evaluation of two serological methods for detecting Treponema pallidum[J]. China Tropical Medicine, 2011, 11(9): 1143-1144
Authors:CHEN Mei-jun  WANG Xin-xin  ZHANG Zhong-ying
Affiliation:CHEN Mei-jun,WANG Xin-xin,ZHANG Zhong-ying.(Clinical laboratory Center,Zhongshan Hospital of Xiamen University,Xiamen 361005,Fujian,P.R.China,Correspondidng author:ZHANG Zhong-ying,E-mail:cmj780721@xmzsh.com)
Abstract:Objective To explore the diagnostic value of TRUST and TPPA in diagnosis of human syphilis and provide experimental theory for the clinical purpose.Methods TRUST and TPPA were used to detect 2 083 serum specimens(including 910 syphilis serum specimens).Results There were 773 positives were detected by TRUSTout of 910 syphilis serum specimens with a positive rates of 84.9 % and a specificity of 96.1%;while there 889 specimens were positive detected by TPPA with the sensitivity and specificity of 98.7 %,there...
Keywords:Syphilis  TRUST  TPPA  Combined detection  
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