脂溢性角化病220例临床和病理分析

目的探讨脂溢性角化病的临床、组织病理特征和诊断情况。方法对220例组织病理学诊断为脂溢性角化病患者的临床资料进行回顾性分析。结果发病者以老年患者居多；男性多于女性；暴露部位比非暴露部位更易发病；病理分型中以棘层肥厚型及角化过度型最为常见；临床诊断易与色素痣、扁平疣、寻常疣、日光性角化病、基底细胞癌、黑素瘤等相混淆，此时诊断主要依靠组织病理学检查。结论脂溢性角化病与性别、年龄、日光照射有关，组织病理学检查在其诊断及鉴别诊断中具有重要意义。

Clinical and pathological analysis on 220 cases of seborrheic keratosis

Objective To explore the clinical and histopathological characteristcs and the diagnosis ststus of seborrheic keratosis （SK）. Methods The clinical datas of 220 patients with SK were analyzed retrospectively. Re- stills The elderly patients accounted for the majority and males were more than females in patients with SK. SK more occurred in exposed parts than non-exposed parts. The most common pathological type was acanthosis and hy- perkeratosis. Clinically, SK was easily confused with nevi, flat warts, common warts, actinic keratoses, basal cell carcinoma, melanoma and so on. The diagnosis depends on the histopathological examination. Conclusion SK is re- lated to gender, age, and sunlight, histopathological examination is important in the diagnosis and differential diagno- sis of SK.