三养胶麦减肥、降脂及降血糖作用的实验研究

目的对三养胶麦成分进行减肥、降血脂、降血糖动物实验研究。方法通过喂养营养饲料建立大鼠肥胖模型,观察三养胶麦成分的减肥作用;通过喂养高脂饲料建立脂代谢紊乱大鼠模型,观察三养胶麦成分的降脂作用;通过尾静脉注射四氧嘧啶制备糖尿病小鼠模型,观察三养胶麦成分的降血糖作用。结果减肥实验中三养胶麦成分各剂量组大鼠体重明显低于模型组,且高、中剂量组体脂及体脂/体重指数明显低于模型组,差异有显著性意义（P〈0.05或P〈0.01）;降脂实验中三养胶麦成分高、中剂量组体重、血清三酰甘油（TG）含量明显低于模型组,差异有显著性（P〈0.05或P〈0.01）;降糖实验中三养胶麦成分高剂量组空腹血糖明显低于模型组,差异有显著性（P〈0.05）,但糖耐量实验中各组AUC没有显著性差异（P〉0.05）。结论三养胶麦成分具有辅助减肥、降血清三酰甘油及降空腹血糖的保健作用。

Weight-losing, hypolipidemic and hypoglycemic effect of Sanyang oat straw

Objective To observe weight-losing,hypolipidemic and hypoglycemic effect of Sanyang oat straw through animal experiments.Methods Weight-losing effect of Sanyang oat straw was observed through obese rat models fed with hyper alimentative feedstuff.The hypolipidemic effect of Sanyang oat straw was observed through the high-fat-induced lipid metabolism disorder rat model.The hypoglycemic effect of Sanyang oat straw was observed through diabetic mouse model induced by tail intravenous injection of alloxan.Results Weight losing experiment showed that the weight of all the Sanyang oat straw dosage groups was slighter than that of the model group.The body fat and the body fat/body mass index of the high and medium dosage groups were significantly less than the model group（P 0.05 or P 0.01）.In the hypolipidemic experiment,weight and triglyceride（TG） in groups with high-and medium-dosage of Sanyang oat straw were significantly lower than those in the model group（P 0.0 5 or P 0.01）.Hypoglycemic experiments indicated that fasting blood-glucose in the high dosage Sanyang oat straw group was obviously lower than that in the model group（P 0.05） while AUC among the groups showed no difference in the oral glucose tolerance test.Conclusion Sanyang oat straw can lose weight,drop serum triglycerides and reduce fasting plasma glucose.